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Association of Kv1.5 and Kv1.3 contributes to the major voltage-dependent K+ channel in macrophages. , Vicente R., J Biol Chem. December 8, 2006; 281 (49): 37675-85.
The flounder organic anion transporter fOat has sequence, function, and substrate specificity similarity to both mammalian Oat1 and Oat3. , Aslamkhan AG., Am J Physiol Regul Integr Comp Physiol. December 1, 2006; 291 (6): R1773-80.
Ancillary subunits and stimulation frequency determine the potency of chromanol 293B block of the KCNQ1 potassium channel. , Bett GC., J Physiol. November 1, 2006; 576 (Pt 3): 755-67.
Functional demonstration of the ability of a primary spermatogonium as a stem cell by tracing a single cell destiny in Xenopus laevis. , Kawasaki T., Dev Growth Differ. October 1, 2006; 48 (8): 525-35.
Morpholin-2-one derivatives as novel selective T-type Ca2+ channel blockers. , Ku IW., Bioorg Med Chem Lett. October 1, 2006; 16 (19): 5244-8.
In vitro modulation of HERG channels by organochlorine solvent trichlormethane as potential explanation for proarrhythmic effects of chloroform. , Scholz EP., Toxicol Lett. August 20, 2006; 165 (2): 156-66.
GABA-site antagonism and pentobarbital actions do not depend on the alpha-subunit type in the recombinant rat GABA receptor. , Rahman M., Acta Physiol (Oxf). August 1, 2006; 187 (4): 479-88.
The epithelial Na+ channel is inhibited by a peptide derived from proteolytic processing of its alpha subunit. , Carattino MD., J Biol Chem. July 7, 2006; 281 (27): 18901-7.
Atypical tetracyclic antidepressant maprotiline is an antagonist at cardiac hERG potassium channels. , Kiesecker C., Naunyn Schmiedebergs Arch Pharmacol. June 1, 2006; 373 (3): 212-20.
Blockade of HERG human K+ channels and IKr of guinea-pig cardiomyocytes by the antipsychotic drug clozapine. , Lee SY., Br J Pharmacol. June 1, 2006; 148 (4): 499-509.
A comparative study of the action of tolperisone on seven different voltage dependent sodium channel isoforms. , Hofer D., Eur J Pharmacol. May 24, 2006; 538 (1-3): 5-14.
Interaction with sigma(1) protein, but not N-methyl-D-aspartate receptor, is involved in the pharmacological activity of donepezil. , Maurice T., J Pharmacol Exp Ther. May 1, 2006; 317 (2): 606-14.
Analyses of dose-response curves to compare the antimicrobial activity of model cationic alpha-helical peptides highlights the necessity for a minimum of two activity parameters. , Rautenbach M., Anal Biochem. March 1, 2006; 350 (1): 81-90.
Drug binding interactions in the inner cavity of HERG channels: molecular insights from structure-activity relationships of clofilium and ibutilide analogs. , Perry M ., Mol Pharmacol. February 1, 2006; 69 (2): 509-19.
Four novel tarantula toxins as selective modulators of voltage-gated sodium channel subtypes. , Bosmans F., Mol Pharmacol. February 1, 2006; 69 (2): 419-29.
The receptor site of the spider toxin PcTx1 on the proton-gated cation channel ASIC1a. , Salinas M., J Physiol. January 15, 2006; 570 (Pt 2): 339-54.
Enantiomers of cis-constrained and flexible 2-substituted GABA analogues exert opposite effects at recombinant GABA(C) receptors. , Crittenden DL., Bioorg Med Chem. January 15, 2006; 14 (2): 447-55.
Molecular identification and functional characterization of a temperature-sensitive transient receptor potential channel ( TRPM8) from canine. , Liu Y ., Eur J Pharmacol. January 13, 2006; 530 (1-2): 23-32.
Block of hERG channel by ziprasidone: biophysical properties and molecular determinants. , Su Z., Biochem Pharmacol. January 12, 2006; 71 (3): 278-86.
Inhibitory modulation of ATP-sensitive potassium channels by gallate-ester moiety of (-)-epigallocatechin-3-gallate. , Baek WK., Biochem Pharmacol. November 25, 2005; 70 (11): 1560-7.
CaMKII tethers to L-type Ca2+ channels, establishing a local and dedicated integrator of Ca2+ signals for facilitation. , Hudmon A., J Cell Biol. November 7, 2005; 171 (3): 537-47.
The beta subunit increases the ginkgolide B sensitivity of inhibitory glycine receptors. , Kondratskaya EL., Neuropharmacology. November 1, 2005; 49 (6): 945-51.
Evans blue is a specific antagonist of the human epithelial Na+ channel delta-subunit. , Yamamura H., J Pharmacol Exp Ther. November 1, 2005; 315 (2): 965-9.
Characteristics of ginsenoside Rg3-mediated brain Na+ current inhibition. , Lee JH , Lee JH ., Mol Pharmacol. October 1, 2005; 68 (4): 1114-26.
A single residue in the S6 transmembrane domain governs the differential flecainide sensitivity of voltage-gated potassium channels. , Herrera D., Mol Pharmacol. August 1, 2005; 68 (2): 305-16.
The dietary polyphenol ellagic acid is a potent inhibitor of hOAT1. , Whitley AC., Drug Metab Dispos. August 1, 2005; 33 (8): 1097-100.
Zinc activates TREK-2 potassium channel activity. , Kim JS ., J Pharmacol Exp Ther. August 1, 2005; 314 (2): 618-25.
The effects of the tramadol metabolite O-desmethyl tramadol on muscarinic receptor-induced responses in Xenopus oocytes expressing cloned M1 or M3 receptors. , Nakamura M., Anesth Analg. July 1, 2005; 101 (1): 180-6, table of contents.
Mutation of the pore glutamate affects both cytoplasmic and external dequalinium block in the rat olfactory CNGA2 channel. , Qu W., Eur Biophys J. July 1, 2005; 34 (5): 442-53.
Inhibition of human ether-a- go-go-related gene K+ channel and IKr of guinea pig cardiomyocytes by antipsychotic drug trifluoperazine. , Choi SY., J Pharmacol Exp Ther. May 1, 2005; 313 (2): 888-95.
Transport of the natural sweetener stevioside and its aglycone steviol by human organic anion transporter (hOAT1; SLC22A6) and hOAT3 ( SLC22A8). , Srimaroeng C., J Pharmacol Exp Ther. May 1, 2005; 313 (2): 621-8.
Molecular dissection of tropisetron, an alpha7 nicotinic acetylcholine receptor-selective partial agonist. , Papke RL., Neurosci Lett. April 22, 2005; 378 (3): 140-4.
ZW10 links mitotic checkpoint signaling to the structural kinetochore. , Kops GJ., J Cell Biol. April 11, 2005; 169 (1): 49-60.
Marine alkaloids (-)-pictamine and (-)-lepadin B block neuronal nicotinic acetylcholine receptors. , Tsuneki H., Biol Pharm Bull. April 1, 2005; 28 (4): 611-4.
Relapsing diabetes can result from moderately activating mutations in KCNJ11. , Gloyn AL., Hum Mol Genet. April 1, 2005; 14 (7): 925-34.
The effects of the neurosteroids: pregnenolone, progesterone and dehydroepiandrosterone on muscarinic receptor-induced responses in Xenopus oocytes expressing M1 and M3 receptors. , Horishita T., Naunyn Schmiedebergs Arch Pharmacol. March 1, 2005; 371 (3): 221-8.
Contrasting the effects of nifedipine on subtypes of endogenous and recombinant T-type Ca2+ channels. , Shcheglovitov A., Biochem Pharmacol. March 1, 2005; 69 (5): 841-54.
The acetylcholinesterase inhibitor BW284c51 is a potent blocker of Torpedo nicotinic AchRs incorporated into the Xenopus oocyte membrane. , Olivera-Bravo S., Br J Pharmacol. January 1, 2005; 144 (1): 88-97.
Class Ia anti-arrhythmic drug ajmaline blocks HERG potassium channels: mode of action. , Kiesecker C., Naunyn Schmiedebergs Arch Pharmacol. December 1, 2004; 370 (6): 423-35.
Block of wild-type and inactivation-deficient human ether-a- go-go-related gene K+ channels by halofantrine. , Sánchez-Chapula JA., Naunyn Schmiedebergs Arch Pharmacol. December 1, 2004; 370 (6): 484-91.
Analysis of the effects of halothane on Gi-coupled muscarinic M2 receptor signaling in Xenopus oocytes using a chimeric G alpha protein. , Minami K., Pharmacology. November 1, 2004; 72 (3): 205-12.
A noncompetitive, sequential mechanism for inhibition of rat alpha4beta2 neuronal nicotinic acetylcholine receptors by carbamate pesticides. , Smulders CJ., Toxicol Sci. November 1, 2004; 82 (1): 219-27.
Inhibitory profile of SEA0400 [2-[4-[(2,5-difluorophenyl)methoxy]phenoxy]-5-ethoxyaniline] assessed on the cardiac Na+-Ca2+ exchanger, NCX1.1. , Lee C , Lee C ., J Pharmacol Exp Ther. November 1, 2004; 311 (2): 748-57.
The dietary flavonoids apigenin and (-)-epigallocatechin gallate enhance the positive modulation by diazepam of the activation by GABA of recombinant GABA(A) receptors. , Campbell EL., Biochem Pharmacol. October 15, 2004; 68 (8): 1631-8.
Automated higher-throughput compound screening on ion channel targets based on the Xenopus laevis oocyte expression system. , Pehl U., Assay Drug Dev Technol. October 1, 2004; 2 (5): 515-24.
State-dependent trapping of flecainide in the cardiac sodium channel. , Ramos E., J Physiol. October 1, 2004; 560 (Pt 1): 37-49.
Linopirdine blocks alpha9alpha10-containing nicotinic cholinergic receptors of cochlear hair cells. , Gomez-Casati ME., J Assoc Res Otolaryngol. September 1, 2004; 5 (3): 261-9.
Effects of the atrial antiarrhythmic drug AVE0118 on cardiac ion channels. , Gögelein H., Naunyn Schmiedebergs Arch Pharmacol. September 1, 2004; 370 (3): 183-92.
Molecular identification and characterization of three isoforms of tachykinin NK(1)-like receptors in the cane toad Bufo marinus. , Liu L., Am J Physiol Regul Integr Comp Physiol. September 1, 2004; 287 (3): R575-85.
The solubilizing detergents, Tween 80 and Triton X-100 non-competitively inhibit alpha 7-nicotinic acetylcholine receptor function in Xenopus oocytes. , Oz M., J Neurosci Methods. August 30, 2004; 137 (2): 167-73.