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Discovery of a genetic module essential for assigning left- right asymmetry in humans and ancestral vertebrates. , Szenker-Ravi E., Nat Genet. January 1, 2022; 54 (1): 62-72.
Enzyme activity and selectivity filter stability of ancient TRPM2 channels were simultaneously lost in early vertebrates. , Iordanov I., Elife. April 2, 2019; 8
Liver Specification in the Absence of Cardiac Differentiation Revealed by Differential Sensitivity to Wnt/β Catenin Pathway Activation. , Haworth K., Front Physiol. January 1, 2019; 10 155.
Identification of retinal homeobox ( rax) gene-dependent genes by a microarray approach: The DNA endoglycosylase neil3 is a major downstream component of the rax genetic pathway. , Pan Y., Dev Dyn. November 1, 2018; 247 (11): 1199-1210.
Retinoic acid-induced expression of Hnf1b and Fzd4 is required for pancreas development in Xenopus laevis. , Gere-Becker MB., Development. June 8, 2018; 145 (12):
Structure of a TRPM2 channel in complex with Ca2+ explains unique gating regulation. , Zhang Z ., Elife. May 10, 2018; 7
The histone methyltransferase Setd7 promotes pancreatic progenitor identity. , Kofent J., Development. October 1, 2016; 143 (19): 3573-3581.
The proposed channel-enzyme transient receptor potential melastatin 2 does not possess ADP ribose hydrolase activity. , Iordanov I., Elife. July 6, 2016; 5
Successful transfer to sulfonylureas in KCNJ11 neonatal diabetes is determined by the mutation and duration of diabetes. , Babiker T., Diabetologia. June 1, 2016; 59 (6): 1162-6.
Xenopus pax6 mutants affect eye development and other organ systems, and have phenotypic similarities to human aniridia patients. , Nakayama T ., Dev Biol. December 15, 2015; 408 (2): 328-44.
Understanding How the Subcommissural Organ and Other Periventricular Secretory Structures Contribute via the Cerebrospinal Fluid to Neurogenesis. , Guerra MM., Front Cell Neurosci. September 23, 2015; 9 480.
Genome-wide view of TGFβ/ Foxh1 regulation of the early mesendoderm program. , Chiu WT ., Development. December 1, 2014; 141 (23): 4537-47.
MicroRNAs are critical regulators of tuberous sclerosis complex and mTORC1 activity in the size control of the Xenopus kidney. , Romaker D., Proc Natl Acad Sci U S A. April 29, 2014; 111 (17): 6335-40.
Characterization of the insulin-like growth factor binding protein family in Xenopus tropicalis. , Haramoto Y ., Int J Dev Biol. January 1, 2014; 58 (9): 705-11.
FGT-1 is a mammalian GLUT2-like facilitative glucose transporter in Caenorhabditis elegans whose malfunction induces fat accumulation in intestinal cells. , Kitaoka S., PLoS One. June 4, 2013; 8 (6): e68475.
Retinoic acid-activated Ndrg1a represses Wnt/ β-catenin signaling to allow Xenopus pancreas, oesophagus, stomach, and duodenum specification. , Zhang T., PLoS One. May 15, 2013; 8 (5): e65058.
Homeoprotein hhex-induced conversion of intestinal to ventral pancreatic precursors results in the formation of giant pancreata in Xenopus embryos. , Zhao H ., Proc Natl Acad Sci U S A. May 29, 2012; 109 (22): 8594-9.
The signaling protein CD38 is essential for early embryonic development. , Churamani D., J Biol Chem. March 2, 2012; 287 (10): 6974-8.
Transient expression of Ngn3 in Xenopus endoderm promotes early and ectopic development of pancreatic beta and delta cells. , Oropeza D., Genesis. March 1, 2012; 50 (3): 271-85.
Xenopus staufen2 is required for anterior endodermal organ formation. , Bilogan CK ., Genesis. March 1, 2012; 50 (3): 251-9.
Roles of major facilitator superfamily transporters in phosphate response in Drosophila. , Bergwitz C., PLoS One. January 1, 2012; 7 (2): e31730.
Xenopus laevis insulin receptor substrate IRS-1 is important for eye development. , Bugner V., Dev Dyn. July 1, 2011; 240 (7): 1705-15.
Functional analysis of Rfx6 and mutant variants associated with neonatal diabetes. , Pearl EJ ., Dev Biol. March 1, 2011; 351 (1): 135-45.
Programming pluripotent precursor cells derived from Xenopus embryos to generate specific tissues and organs. , Borchers A ., Genes (Basel). November 18, 2010; 1 (3): 413-26.
Arp2/3- and cofilin-coordinated actin dynamics is required for insulin-mediated GLUT4 translocation to the surface of muscle cells. , Chiu TT., Mol Biol Cell. October 15, 2010; 21 (20): 3529-39.
Appl1 is essential for the survival of Xenopus pancreas, duodenum, and stomach progenitor cells. , Wen L., Dev Dyn. August 1, 2010; 239 (8): 2198-207.
Xenopus insm1 is essential for gastrointestinal and pancreatic endocrine cell development. , Horb LD ., Dev Dyn. October 1, 2009; 238 (10): 2505-10.
Xenopus pancreas development. , Pearl EJ ., Dev Dyn. June 1, 2009; 238 (6): 1271-86.
The tetraspanin Tm4sf3 is localized to the ventral pancreas and regulates fusion of the dorsal and ventral pancreatic buds. , Jarikji Z ., Development. June 1, 2009; 136 (11): 1791-800.
IGFBP-4 is an inhibitor of canonical Wnt signalling required for cardiogenesis. , Zhu W., Nature. July 17, 2008; 454 (7202): 345-9.
The Gata5 target, TGIF2, defines the pancreatic region by modulating BMP signals within the endoderm. , Spagnoli FM ., Development. February 1, 2008; 135 (3): 451-61.
Sulfonylurea receptors type 1 and 2A randomly assemble to form heteromeric KATP channels of mixed subunit composition. , Chan KW., J Gen Physiol. January 1, 2008; 131 (1): 43-58.
The secreted serine protease xHtrA1 stimulates long-range FGF signaling in the early Xenopus embryo. , Hou S., Dev Cell. August 1, 2007; 13 (2): 226-41.
Retinoic acid-mediated patterning of the pre-pancreatic endoderm in Xenopus operates via direct and indirect mechanisms. , Pan FC., Mech Dev. August 1, 2007; 124 (7-8): 518-31.
Differential ability of Ptf1a and Ptf1a-VP16 to convert stomach, duodenum and liver to pancreas. , Jarikji ZH ., Dev Biol. April 15, 2007; 304 (2): 786-99.
PP2A:B56epsilon is required for eye induction and eye field separation. , Rorick AM., Dev Biol. February 15, 2007; 302 (2): 477-93.
Characterization of the agr2 gene, a homologue of X. laevis anterior gradient 2, from the zebrafish, Danio rerio. , Shih LJ., Gene Expr Patterns. February 1, 2007; 7 (4): 452-60.
Expression analysis of IGFBP-rP10, IGFBP-like and Mig30 in early Xenopus development. , Kuerner KM., Dev Dyn. October 1, 2006; 235 (10): 2861-7.
Combined ectopic expression of Pdx1 and Ptf1a/p48 results in the stable conversion of posterior endoderm into endocrine and exocrine pancreatic tissue. , Afelik S., Genes Dev. June 1, 2006; 20 (11): 1441-6.
The RNA-binding protein, Vg1RBP, is required for pancreatic fate specification. , Spagnoli FM ., Dev Biol. April 15, 2006; 292 (2): 442-56.
A repeated IMP-binding motif controls oskar mRNA translation and anchoring independently of Drosophila melanogaster IMP. , Munro TP., J Cell Biol. February 13, 2006; 172 (4): 577-88.
Wnt5 signaling in vertebrate pancreas development. , Kim HJ ., BMC Biol. October 24, 2005; 3 23.
Connective- tissue growth factor modulates WNT signalling and interacts with the WNT receptor complex. , Mercurio S., Development. May 1, 2004; 131 (9): 2137-47.
Pancreatic protein disulfide isomerase ( XPDIp) is an early marker for the exocrine lineage of the developing pancreas in Xenopus laevis embryos. , Afelik S., Gene Expr Patterns. January 1, 2004; 4 (1): 71-6.
Insulin signaling inhibits the 5-HT2C receptor in choroid plexus via MAP kinase. , Hurley JH., BMC Neurosci. June 9, 2003; 4 10.
Xenopus Cyr61 regulates gastrulation movements and modulates Wnt signalling. , Latinkic BV ., Development. June 1, 2003; 130 (11): 2429-41.
Cell-autonomous and signal-dependent expression of liver and intestine marker genes in pluripotent precursor cells from Xenopus embryos. , Chen Y , Chen Y ., Mech Dev. March 1, 2003; 120 (3): 277-88.
The IGF pathway regulates head formation by inhibiting Wnt signaling in Xenopus. , Richard-Parpaillon L ., Dev Biol. April 15, 2002; 244 (2): 407-17.
Overexpression of the secreted factor Mig30 expressed in the Spemann organizer impairs morphogenetic movements during Xenopus gastrulation. , Hayata T., Mech Dev. March 1, 2002; 112 (1-2): 37-51.
Open state destabilization by ATP occupancy is mechanism speeding burst exit underlying KATP channel inhibition by ATP. , Li L., J Gen Physiol. January 1, 2002; 119 (1): 105-16.