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A tryptophan residue (W736) in the amino-terminus of the P-segment of domain II is involved in pore formation in Na(v)1.4 voltage-gated sodium channels. , Carbonneau E., Pflugers Arch. October 1, 2002; 445 (1): 18-24.
Role of outer ring carboxylates of the rat skeletal muscle sodium channel pore in proton block. , Khan A., J Physiol. August 15, 2002; 543 (Pt 1): 71-84.
Energetic localization of saxitoxin in its channel binding site. , Choudhary G., Biophys J. August 1, 2002; 83 (2): 912-9.
The Dlx5 homeobox gene is essential for vestibular morphogenesis in the mouse embryo through a BMP4-mediated pathway. , Merlo GR., Dev Biol. August 1, 2002; 248 (1): 157-69.
Spermine block of the strong inward rectifier potassium channel Kir2.1: dual roles of surface charge screening and pore block. , Xie LH., J Gen Physiol. July 1, 2002; 120 (1): 53-66.
Cocaine binds to a common site on open and inactivated human heart ( Na(v)1.5) sodium channels. , O'Leary ME., J Physiol. June 15, 2002; 541 (Pt 3): 701-16.
Role of anion-cation interactions on the pre-steady-state currents of the rat Na(+)-Cl(-)-dependent GABA cotransporter rGAT1. , Bossi E ., J Physiol. June 1, 2002; 541 (Pt 2): 343-50.
Effects of clomipramine on neuronal nicotinic acetylcholine receptors. , López-Valdés HE., Eur J Pharmacol. May 24, 2002; 444 (1-2): 13-9.
The alpha9alpha10 nicotinic acetylcholine receptor is permeable to and is modulated by divalent cations. , Weisstaub N., Hear Res. May 1, 2002; 167 (1-2): 122-35.
Channel blockers acting at N-methyl-D-aspartate receptors: differential effects of mutations in the vestibule and ion channel pore. , Kashiwagi K ., Mol Pharmacol. March 1, 2002; 61 (3): 533-45.
Molecular rearrangements of the extracellular vestibule in NMDAR channels during gating. , Sobolevsky AI., Neuron. January 3, 2002; 33 (1): 75-85.
A novel human nicotinic receptor subunit, alpha10, that confers functionality to the alpha9-subunit. , Sgard F., Mol Pharmacol. January 1, 2002; 61 (1): 150-9.
Designed peptide analogues of the potassium channel blocker ShK toxin. , Lanigan MD., Biochemistry. December 25, 2001; 40 (51): 15528-37.
Mutation K448E in the external loop 5 of rat GABA transporter rGAT1 induces pH sensitivity and alters substrate interactions. , Forlani G., J Physiol. October 15, 2001; 536 (Pt 2): 479-94.
Exploration of the pore structure of a peptide-gated Na+ channel. , Poët M., EMBO J. October 15, 2001; 20 (20): 5595-602.
CFTR: covalent and noncovalent modification suggests a role for fixed charges in anion conduction. , Smith SS., J Gen Physiol. October 1, 2001; 118 (4): 407-31.
Antagonism of nicotinic acetylcholine receptors by inhibitors of monoamine uptake. , López-Valdés HE., Mol Psychiatry. September 1, 2001; 6 (5): 511-9.
The selectivity filter of the voltage-gated sodium channel is involved in channel activation. , Hilber K., J Biol Chem. July 27, 2001; 276 (30): 27831-9.
Memantine inhibits efferent cholinergic transmission in the cochlea by blocking nicotinic acetylcholine receptors of outer hair cells. , Oliver D., Mol Pharmacol. July 1, 2001; 60 (1): 183-9.
Channel-lining residues of the AMPA receptor M2 segment: structural environment of the Q/R site and identification of the selectivity filter. , Kuner T., J Neurosci. June 15, 2001; 21 (12): 4162-72.
Conformational changes in S6 coupled to the opening of cyclic nucleotide-gated channels. , Flynn GE., Neuron. June 1, 2001; 30 (3): 689-98.
Functional properties of a truncated recombinant GIRK5 potassium channel. , Salvador C., Biochim Biophys Acta. May 2, 2001; 1512 (1): 135-47.
Structural and gating changes of the sodium channel induced by mutation of a residue in the upper third of IVS6, creating an external access path for local anesthetics. , Sunami A., Mol Pharmacol. April 1, 2001; 59 (4): 684-91.
Titration of tertiapin-Q inhibition of ROMK1 channels by extracellular protons. , Ramu Y., Biochemistry. March 27, 2001; 40 (12): 3601-5.
Control of rectification and permeation by two distinct sites after the second transmembrane region in Kir2.1 K+ channel. , Kubo Y., J Physiol. March 15, 2001; 531 (Pt 3): 645-60.
Specific neosaxitoxin interactions with the Na+ channel outer vestibule determined by mutant cycle analysis. , Penzotti JL., Biophys J. February 1, 2001; 80 (2): 698-706.
Modulation of alpha2beta4 neuronal nicotinic acetylcholine receptors by zinc. , García-Colunga J., Neuroreport. January 22, 2001; 12 (1): 147-50.
Gating induces a conformational change in the outer vestibule of ENaC. , Snyder PM ., J Gen Physiol. December 1, 2000; 116 (6): 781-90.
The role of positively charged amino acids in ATP recognition by human P2X(1) receptors. , Ennion S., J Biol Chem. September 22, 2000; 275 (38): 29361-7.
Structure of the amino terminus of a gap junction protein. , Purnick PE., Arch Biochem Biophys. September 15, 2000; 381 (2): 181-90.
mRNA expression of kidney-specific ClC-K1 chloride channel in single-cell reverse transcription-polymerase chain reaction analysis of outer hair cells of rat cochlea. , Kawasaki E., Neurosci Lett. August 18, 2000; 290 (1): 76-8.
Glycoside binding and translocation in Na(+)-dependent glucose cotransporters: comparison of SGLT1 and SGLT3. , Díez-Sampedro A., J Membr Biol. July 15, 2000; 176 (2): 111-7.
Calcitonin gene-related peptide suppresses hair cell responses to mechanical stimulation in the Xenopus lateral line organ. , Bailey GP., J Neurosci. July 1, 2000; 20 (13): 5163-9.
mRNA encoding 'ClC-K1, a kidney Cl(-)- channel' is expressed in marginal cells of the stria vascularis of rat cochlea: its possible contribution to Cl(-) currents. , Ando M., Neurosci Lett. April 28, 2000; 284 (3): 171-4.
Cloning and expression of the alpha9 nicotinic acetylcholine receptor subunit in cochlear hair cells of the chick. , Hiel H., Dev Biol. March 6, 2000; 858 (1): 215-25.
High calcium permeability and calcium block of the alpha9 nicotinic acetylcholine receptor. , Katz E., Hear Res. March 1, 2000; 141 (1-2): 117-28.
Trapping of a methanesulfonanilide by closure of the HERG potassium channel activation gate. , Mitcheson JS., J Gen Physiol. March 1, 2000; 115 (3): 229-40.
A critical residue for isoform difference in tetrodotoxin affinity is a molecular determinant of the external access path for local anesthetics in the cardiac sodium channel. , Sunami A., Proc Natl Acad Sci U S A. February 29, 2000; 97 (5): 2326-31.
Deletion of the S3-S4 linker in the Shaker potassium channel reveals two quenching groups near the outside of S4. , Sørensen JB., J Gen Physiol. February 1, 2000; 115 (2): 209-22.
Otx1 gene-controlled morphogenesis of the horizontal semicircular canal and the origin of the gnathostome characteristics. , Mazan S., Evol Dev. January 1, 2000; 2 (4): 186-93.
Human pendrin expressed in Xenopus laevis oocytes mediates chloride/formate exchange. , Scott DA., Am J Physiol Cell Physiol. January 1, 2000; 278 (1): C207-11.
Gating and flickery block differentially affected by rubidium in homomeric KCNQ1 and heteromeric KCNQ1/ KCNE1 potassium channels. , Pusch M., Biophys J. January 1, 2000; 78 (1): 211-26.
Identification of transduction elements for benzodiazepine modulation of the GABA(A) receptor: three residues are required for allosteric coupling. , Boileau AJ., J Neurosci. December 1, 1999; 19 (23): 10213-20.
Inward rectifier potassium channel Kir 2.3 is inhibited by internal sulfhydryl modification. , Radeke CM., Neuroreport. November 8, 1999; 10 (16): 3277-82.
Mechanisms of inward-rectifier K+ channel inhibition by tertiapin-Q. , Jin W., Biochemistry. October 26, 1999; 38 (43): 14294-301.
Cytoplasmic amino and carboxyl domains form a wide intracellular vestibule in an inwardly rectifying potassium channel. , Lu T., Proc Natl Acad Sci U S A. August 17, 1999; 96 (17): 9926-31.
The role of Ca2+-activated K+ channel spliced variants in the tonotopic organization of the turtle cochlea. , Jones EM., J Physiol. August 1, 1999; 518 ( Pt 3) 653-65.
Bicuculline block of small-conductance calcium-activated potassium channels. , Khawaled R., Pflugers Arch. August 1, 1999; 438 (3): 314-21.
A marine snail neurotoxin shares with scorpion toxins a convergent mechanism of blockade on the pore of voltage-gated K channels. , García E., J Gen Physiol. July 1, 1999; 114 (1): 141-57.
On the molecular basis of ion permeation in the epithelial Na+ channel. , Kellenberger S., J Gen Physiol. July 1, 1999; 114 (1): 13-30.