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Bumepamine, a brain-permeant benzylamine derivative of bumetanide, does not inhibit NKCC1 but is more potent to enhance phenobarbital's anti-seizure efficacy. , Brandt C., Neuropharmacology. December 1, 2018; 143 186-204.
Azosemide is more potent than bumetanide and various other loop diuretics to inhibit the sodium-potassium-chloride-cotransporter human variants hNKCC1A and hNKCC1B. , Hampel P., Sci Rep. June 29, 2018; 8 (1): 9877.
Cotransporter-mediated water transport underlying cerebrospinal fluid formation. , Steffensen AB., Nat Commun. June 4, 2018; 9 (1): 2167.
The Na+:Cl- cotransporter is activated and phosphorylated at the amino-terminal domain upon intracellular chloride depletion. , Pacheco-Alvarez D., J Biol Chem. September 29, 2006; 281 (39): 28755-63.
WNK3 bypasses the tonicity requirement for K-Cl cotransporter activation via a phosphatase-dependent pathway. , de Los Heros P., Proc Natl Acad Sci U S A. February 7, 2006; 103 (6): 1976-81.
WNK4 regulates apical and basolateral Cl- flux in extrarenal epithelia. , Kahle KT., Proc Natl Acad Sci U S A. February 17, 2004; 101 (7): 2064-9.