Papers associated with heart (and nkx2-5)

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	XNkx-2.5, a Xenopus gene related to Nkx-2.5 and tinman: evidence for a conserved role in cardiac development., Tonissen KF., Dev Biol. March 1, 1994; 162 (1): 325-8.
	Assignment of cardiac homeobox gene CSX to human chromosome 5q34., Shiojima I., Genomics. May 1, 1995; 27 (1): 204-6.
	Identification of novel DNA binding targets and regulatory domains of a murine tinman homeodomain factor, nkx-2.5., Chen CY., J Biol Chem. June 30, 1995; 270 (26): 15628-33.
	tinman, a Drosophila homeobox gene required for heart and visceral mesoderm specification, may be represented by a family of genes in vertebrates: XNkx-2.3, a second vertebrate homologue of tinman., Evans SM., Development. November 1, 1995; 121 (11): 3889-99.
	Induction of avian cardiac myogenesis by anterior endoderm., Schultheiss TM., Development. December 1, 1995; 121 (12): 4203-14.
	Molecular cloning, chromosomal mapping, and characterization of the human cardiac-specific homeobox gene hCsx., Turbay D., Mol Med. January 1, 1996; 2 (1): 86-96.
	Activation of the cardiac alpha-actin promoter depends upon serum response factor, Tinman homologue, Nkx-2.5, and intact serum response elements., Chen CY., Dev Genet. January 1, 1996; 19 (2): 119-30.
	Chick NKx-2.3 represents a novel family member of vertebrate homologues to the Drosophila homeobox gene tinman: differential expression of cNKx-2.3 and cNKx-2.5 during heart and gut development., Buchberger A., Mech Dev. May 1, 1996; 56 (1-2): 151-63.
	The atrial natriuretic factor promoter is a downstream target for Nkx-2.5 in the myocardium., Durocher D., Mol Cell Biol. September 1, 1996; 16 (9): 4648-55.
	Overexpression of the tinman-related genes XNkx-2.5 and XNkx-2.3 in Xenopus embryos results in myocardial hyperplasia., Cleaver OB., Development. November 1, 1996; 122 (11): 3549-56.
	Recruitment of the tinman homolog Nkx-2.5 by serum response factor activates cardiac alpha-actin gene transcription., Chen CY., Mol Cell Biol. November 1, 1996; 16 (11): 6372-84.
	Zebrafish tinman homolog demarcates the heart field and initiates myocardial differentiation., Chen JN., Development. December 1, 1996; 122 (12): 3809-16.
	A new tinman-related gene, nkx2.7, anticipates the expression of nkx2.5 and nkx2.3 in zebrafish heart and pharyngeal endoderm., Lee KH., Dev Biol. December 15, 1996; 180 (2): 722-31.
	Over-expression of GATA-6 in Xenopus embryos blocks differentiation of heart precursors., Gove C., EMBO J. January 15, 1997; 16 (2): 355-68.
	CARP, a cardiac ankyrin repeat protein, is downstream in the Nkx2-5 homeobox gene pathway., Zou Y., Development. February 1, 1997; 124 (4): 793-804.
	Homeodomain factor Nkx2-5 controls left/right asymmetric expression of bHLH gene eHand during murine heart development., Biben C., Genes Dev. June 1, 1997; 11 (11): 1357-69.
	Competition between negative acting YY1 versus positive acting serum response factor and tinman homologue Nkx-2.5 regulates cardiac alpha-actin promoter activity., Chen CY., Mol Endocrinol. June 1, 1997; 11 (6): 812-22.
	Retinoic acid can block differentiation of the myocardium after heart specification., Drysdale TA., Dev Biol. August 15, 1997; 188 (2): 205-15.
	The cardiac transcription factors Nkx2-5 and GATA-4 are mutual cofactors., Durocher D., EMBO J. September 15, 1997; 16 (18): 5687-96.
	Vertebrate homologs of tinman and bagpipe: roles of the homeobox genes in cardiovascular development., Tanaka M., Dev Genet. January 1, 1998; 22 (3): 239-49.
	tinman-related genes expressed during heart development in Xenopus., Newman CS., Dev Genet. January 1, 1998; 22 (3): 230-8.
	Homeobox genes in cardiovascular development., Patterson KD., Curr Top Dev Biol. January 1, 1998; 40 1-44.
	Murine cerberus homologue mCer-1: a candidate anterior patterning molecule., Biben C., Dev Biol. February 15, 1998; 194 (2): 135-51.
	Congenital heart disease caused by mutations in the transcription factor NKX2-5., Schott JJ., Science. July 3, 1998; 281 (5373): 108-11.
	Divergent roles for NK-2 class homeobox genes in cardiogenesis in flies and mice., Ranganayakulu G., Development. August 1, 1998; 125 (16): 3037-48.
	A GATA-dependent nkx-2.5 regulatory element activates early cardiac gene expression in transgenic mice., Searcy RD., Development. November 1, 1998; 125 (22): 4461-70.
	Vertebrate tinman homologues XNkx2-3 and XNkx2-5 are required for heart formation in a functionally redundant manner., Fu Y., Development. November 1, 1998; 125 (22): 4439-49.
	Tinman function is essential for vertebrate heart development: elimination of cardiac differentiation by dominant inhibitory mutants of the tinman-related genes, XNkx2-3 and XNkx2-5., Grow MW., Dev Biol. December 1, 1998; 204 (1): 187-96.
	Identification of the in vivo casein kinase II phosphorylation site within the homeodomain of the cardiac tisue-specifying homeobox gene product Csx/Nkx2.5., Kasahara H., Mol Cell Biol. January 1, 1999; 19 (1): 526-36.
	Control of early cardiac-specific transcription of Nkx2-5 by a GATA-dependent enhancer., Lien CL., Development. January 1, 1999; 126 (1): 75-84.
	Seeking a regulatory roadmap for heart morphogenesis., Harvey RP., Semin Cell Dev Biol. February 1, 1999; 10 (1): 99-107.
	Vertebrate tinman homologues and cardiac differentiation., Evans SM., Semin Cell Dev Biol. February 1, 1999; 10 (1): 73-83.
	Identification of upstream regulatory regions in the heart-expressed homeobox gene Nkx2-5., Reecy JM., Development. February 1, 1999; 126 (4): 839-49.
	The cardiac homeobox gene Csx/Nkx2.5 lies genetically upstream of multiple genes essential for heart development., Tanaka M., Development. March 1, 1999; 126 (6): 1269-80.
	Tbx5 is essential for heart development., Horb ME., Development. April 1, 1999; 126 (8): 1739-51.
	Complex modular cis-acting elements regulate expression of the cardiac specifying homeobox gene Csx/Nkx2.5., Tanaka M., Development. April 1, 1999; 126 (7): 1439-50.
	Characterization of the murine A1 adenosine receptor promoter, potent regulation by GATA-4 and Nkx2.5., Rivkees SA., J Biol Chem. May 14, 1999; 274 (20): 14204-9.
	Amphibian embryos as a model system for organ engineering: in vitro induction and rescue of the heart anlage., Grunz H., Int J Dev Biol. July 1, 1999; 43 (4): 361-4.
	Bone morphogenetic proteins induce cardiomyocyte differentiation through the mitogen-activated protein kinase kinase kinase TAK1 and cardiac transcription factors Csx/Nkx-2.5 and GATA-4., Monzen K., Mol Cell Biol. October 1, 1999; 19 (10): 7096-105.
	Building the heart piece by piece: modularity of cis-elements regulating Nkx2-5 transcription., Schwartz RJ., Development. October 1, 1999; 126 (19): 4187-92.
	Gata5 is required for the development of the heart and endoderm in zebrafish., Reiter JF., Genes Dev. November 15, 1999; 13 (22): 2983-95.
	A role for GATA-4/5/6 in the regulation of Nkx2.5 expression with implications for patterning of the precardiac field., Jiang Y., Dev Biol. December 1, 1999; 216 (1): 57-71.
	Mutations in the cardiac transcription factor NKX2.5 affect diverse cardiac developmental pathways., Benson DW., J Clin Invest. December 1, 1999; 104 (11): 1567-73.
	Direct activation of a GATA6 cardiac enhancer by Nkx2.5: evidence for a reinforcing regulatory network of Nkx2.5 and GATA transcription factors in the developing heart., Molkentin JD., Dev Biol. January 15, 2000; 217 (2): 301-9.
	Cardiac expression of the ventricle-specific homeobox gene Irx4 is modulated by Nkx2-5 and dHand., Bruneau BG., Dev Biol. January 15, 2000; 217 (2): 266-77.
	The morphology of heart development in Xenopus laevis., Mohun TJ., Dev Biol. February 1, 2000; 218 (1): 74-88.
	Subdivision of the cardiac Nkx2.5 expression domain into myogenic and nonmyogenic compartments., Raffin M., Dev Biol. February 15, 2000; 218 (2): 326-40.
	Transient cardiac expression of the tinman-family homeobox gene, XNkx2-10., Newman CS., Mech Dev. March 1, 2000; 91 (1-2): 369-73.
	Up-regulation of natriuretic peptides in the ventricle of Csx/Nkx2-5 transgenic mice., Takimoto E., Biochem Biophys Res Commun. April 21, 2000; 270 (3): 1074-9.
	Loss of function and inhibitory effects of human CSX/NKX2.5 homeoprotein mutations associated with congenital heart disease., Kasahara H., J Clin Invest. July 1, 2000; 106 (2): 299-308.

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