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A polycystin-2 protein with modified channel properties leads to an increased diameter of renal tubules and to renal cysts. , Grosch M., J Cell Sci. August 15, 2021; 134 (16):
Modeling congenital kidney diseases in Xenopus laevis. , Blackburn ATM., Dis Model Mech. April 9, 2019; 12 (4):
Characterization of potential TRPP2 regulating proteins in early Xenopus embryos. , Futel M., J Cell Biochem. December 1, 2018; 119 (12): 10338-10350.
Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels. , Zheng W., Nat Commun. June 13, 2018; 9 (1): 2302.
Polycystin 1 loss of function is directly linked to an imbalance in G-protein signaling in the kidney. , Zhang B., Development. March 22, 2018; 145 (6):
Native polycystin 2 functions as a plasma membrane Ca2+-permeable cation channel in renal epithelia. , Luo Y., Mol Cell Biol. April 1, 2003; 23 (7): 2600-7.
Polycystin-2 associates with tropomyosin-1, an actin microfilament component. , Li Q ., J Mol Biol. January 31, 2003; 325 (5): 949-62.