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Unique variants in CLCN3, encoding an endosomal anion/proton exchanger, underlie a spectrum of neurodevelopmental disorders. , Duncan AR., Am J Hum Genet. August 5, 2021; 108 (8): 1450-1465.
GluN2A and GluN2B NMDA receptors use distinct allosteric routes. , Tian M., Nat Commun. August 5, 2021; 12 (1): 4709.
Retinol binding protein 1 affects Xenopus anterior neural development via all-trans retinoic acid signaling. , Flach H., Dev Dyn. August 1, 2021; 250 (8): 1096-1112.
Protein kinase D1 variant associated with human epilepsy and peripheral nerve hypermyelination. , Omer S., Clin Genet. August 1, 2021; 100 (2): 176-186.
Bisphenols disrupt thyroid hormone (TH) signaling in the brain and affect TH-dependent brain development in Xenopus laevis. , Niu Y., Aquat Toxicol. August 1, 2021; 237 105902.
Conserved role of the urotensin II receptor 4 signalling pathway to control body straightness in a tetrapod. , Alejevski F., Open Biol. August 1, 2021; 11 (8): 210065.
The Extended Amphibian Metamorphosis Assay: A Thyroid-Specific and Less Animal-Intensive Alternative to the Larval Amphibian Growth and Development Assay. , Ortego LS., Environ Toxicol Chem. August 1, 2021; 40 (8): 2135-2144.
Glycine agonism in ionotropic glutamate receptors. , Stroebel D., Neuropharmacology. August 1, 2021; 193 108631.
Role of matrix metalloproteinase-9 in neurodevelopmental deficits and experience-dependent plasticity in Xenopus laevis. , Gore SV., Elife. July 20, 2021; 10
Early Developmental Exposure to Fluoxetine and Citalopram Results in Different Neurodevelopmental Outcomes. , Liu K ., Neuroscience. July 15, 2021; 467 110-121.
Rab7 is required for mesoderm patterning and gastrulation in Xenopus. , Kreis J., Biol Open. July 15, 2021; 10 (7):
Tau, XMAP215/Msps and Eb1 co-operate interdependently to regulate microtubule polymerisation and bundle formation in axons. , Hahn I., PLoS Genet. July 6, 2021; 17 (7): e1009647.
Axon terminals control endolysosome diffusion to support synaptic remodelling. , Terni B., Life Sci Alliance. July 5, 2021; 4 (8):
The role of cell lineage in the development of neuronal circuitry and function. , Hartenstein V., Dev Biol. July 1, 2021; 475 165-180.
DLG5 variants are associated with multiple congenital anomalies including ciliopathy phenotypes. , Marquez J ., J Med Genet. July 1, 2021; 58 (7): 453-464.
Three-dimensional folding dynamics of the Xenopus tropicalis genome. , Niu L., Nat Genet. July 1, 2021; 53 (7): 1075-1087.
Recurrent seizure-related GRIN1 variant: Molecular mechanism and targeted therapy. , Xu Y ., Ann Clin Transl Neurol. July 1, 2021; 8 (7): 1480-1494.
Fosl1 is vital to heart regeneration upon apex resection in adult Xenopus tropicalis. , Wu HY., NPJ Regen Med. June 29, 2021; 6 (1): 36.
The gastrin-releasing peptide/bombesin system revisited by a reverse-evolutionary study considering Xenopus. , Hirooka A., Sci Rep. June 25, 2021; 11 (1): 13315.
The highly conserved FOXJ1 target CFAP161 is dispensable for motile ciliary function in mouse and Xenopus. , Beckers A., Sci Rep. June 25, 2021; 11 (1): 13333.
Application of Recombinant Rabies Virus to Xenopus Tadpole Brain. , Faulkner RL., eNeuro. June 7, 2021; 8 (4):
Insights from a vertebrate model organism on the molecular mechanisms of whole-body dehydration tolerance. , Luu BE., Mol Cell Biochem. June 1, 2021; 476 (6): 2381-2392.
Electrophysiological Recording for Study of Xenopus Retinotectal Circuitry. , Luo Y., Cold Spring Harb Protoc. June 1, 2021; 2021 (6):
Anaplastic lymphoma kinase (alk), a neuroblastoma associated gene, is expressed in neural crest domains during embryonic development of Xenopus. , Moreno MM., Gene Expr Patterns. June 1, 2021; 40 119183.
Altering metabolite distribution at Xenopus cleavage stages affects left- right gene expression asymmetries. , Onjiko RM., Genesis. June 1, 2021; 59 (5-6): e23418.
Thyroid Disrupting Chemicals in Mixture Perturb Thymocyte Differentiation in Xenopus laevis Tadpoles. , McGuire CC., Toxicol Sci. May 27, 2021; 181 (2): 262-272.
The cytokine FAM3B/PANDER is an FGFR ligand that promotes posterior development in Xenopus. , Zhang F., Proc Natl Acad Sci U S A. May 18, 2021; 118 (20):
Modulating the voltage sensor of a cardiac potassium channel shows antiarrhythmic effects. , Lin Y., Proc Natl Acad Sci U S A. May 18, 2021; 118 (20):
Novel KCND3 Variant Underlying Nonprogressive Congenital Ataxia or SCA19/22 Disrupt KV4.3 Protein Expression and K+ Currents with Variable Effects on Channel Properties. , Zanni G., Int J Mol Sci. May 7, 2021; 22 (9):
Mapping single-cell atlases throughout Metazoa unravels cell type evolution. , Tarashansky AJ., Elife. May 4, 2021; 10
Chronic Exposure to Two Gestagens Differentially Alters Morphology and Gene Expression in Silurana tropicalis. , Thomson P., Arch Environ Contam Toxicol. May 1, 2021; 80 (4): 745-759.
The Negative Allosteric Modulator EU1794-4 Reduces Single-Channel Conductance and Ca2+ Permeability of GluN1/GluN2A N-Methyl-d-Aspartate Receptors. , Perszyk RE., Mol Pharmacol. May 1, 2021; 99 (5): 399-411.
Neurotoxic and convulsant effects induced by jack bean ureases on the mammalian nervous system. , Almeida CGM., Toxicology. April 30, 2021; 454 152737.
WIN55,212-2, a Dual Modulator of Cannabinoid Receptors and G Protein-Coupled Inward Rectifier Potassium Channels. , An D., Biomedicines. April 28, 2021; 9 (5):
Basmisanil, a highly selective GABAA-α5 negative allosteric modulator: preclinical pharmacology and demonstration of functional target engagement in man. , Hipp JF., Sci Rep. April 8, 2021; 11 (1): 7700.
Functional assessment of the "two-hit" model for neurodevelopmental defects in Drosophila and X. laevis. , Pizzo L., PLoS Genet. April 5, 2021; 17 (4): e1009112.
Analysis of Visual Collision Avoidance in Xenopus Tadpoles. , Khakhalin AS ., Cold Spring Harb Protoc. April 1, 2021; 2021 (4):
Expansion of NEUROD2 phenotypes to include developmental delay without seizures. , Mis EK., Am J Med Genet A. April 1, 2021; 185 (4): 1076-1080.
Imaging Mitochondrial Dynamics in the Xenopus Central Nervous System (CNS). , Feng MS., Cold Spring Harb Protoc. April 1, 2021; 2021 (4):
Microglial trogocytosis and the complement system regulate axonal pruning in vivo. , Lim TK., Elife. March 16, 2021; 10
Parallel in vivo analysis of large-effect autism genes implicates cortical neurogenesis and estrogen in risk and resilience. , Willsey HR ., Neuron. March 3, 2021; 109 (5): 788-804.e8.
Light-regulated voltage-gated potassium channels for acute interrogation of channel function in neurons and behavior. , Jerng HH., PLoS One. March 3, 2021; 16 (3): e0248688.
Mutations in PRDM15 Are a Novel Cause of Galloway-Mowat Syndrome. , Mann N., J Am Soc Nephrol. March 1, 2021; 32 (3): 580-596.
Glutamate transporters have a chloride channel with two hydrophobic gates. , Chen I., Nature. March 1, 2021; 591 (7849): 327-331.
Segregation of brain and organizer precursors is differentially regulated by Nodal signaling at blastula stage. , Castro Colabianchi AM., Biol Open. February 25, 2021; 10 (2):
Synthesis and Pharmacological Evaluation of Novel Non-nucleotide Purine Derivatives as P2X7 Antagonists for the Treatment of Neuroinflammation. , Calzaferri F., J Med Chem. February 25, 2021; 64 (4): 2272-2290.
Biallelic variants in COPB1 cause a novel, severe intellectual disability syndrome with cataracts and variable microcephaly. , Macken WL., Genome Med. February 25, 2021; 13 (1): 34.
Differential Regulation of Human Serotonin Receptor Type 3A by Chanoclavine and Ergonovine. , Eom S., Molecules. February 24, 2021; 26 (5):
Ultrasound activates mechanosensitive TRAAK K+ channels through the lipid membrane. , Sorum B., Proc Natl Acad Sci U S A. February 9, 2021; 118 (6):
Rab11fip5 regulates telencephalon development via ephrinB1 recycling. , Yoon J., Development. February 2, 2021; 148 (3):