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Summary Anatomy Item Literature (4079) Expression Attributions Wiki
XB-ANAT-86

Papers associated with tail region (and kcnh2)

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HERG channel inhibitors in extracts of Coptidis rhizoma., Schramm A., Planta Med. May 1, 2011; 77 (7): 692-7.


hERG potassium channel gating is mediated by N- and C-terminal region interactions., Gustina AS., J Gen Physiol. March 1, 2011; 137 (3): 315-25.              


Response of i(kr) and HERG currents to the antipsychotics tiapride and sulpiride., Jo SH., Korean J Physiol Pharmacol. October 1, 2010; 14 (5): 305-10.


Fluorescence-tracking of activation gating in human ERG channels reveals rapid S4 movement and slow pore opening., Es-Salah-Lamoureux Z., PLoS One. May 3, 2010; 5 (5): e10876.                    


Block of the human ether-a-go-go-related gene (hERG) K+ channel by the antidepressant desipramine., Hong HK., Biochem Biophys Res Commun. April 9, 2010; 394 (3): 536-41.


Inhibition of the human ether-a-go-go-related gene (HERG) K+ channels by Lindera erythrocarpa., Hong HK., J Korean Med Sci. December 1, 2009; 24 (6): 1089-98.            


H(1) antihistamine drug promethazine directly blocks hERG K(+) channel., Jo SH., Pharmacol Res. November 1, 2009; 60 (5): 429-37.


A recombinant N-terminal domain fully restores deactivation gating in N-truncated and long QT syndrome mutant hERG potassium channels., Gustina AS., Proc Natl Acad Sci U S A. August 4, 2009; 106 (31): 13082-7.          


Block of HERG k channel by classic histamine h(1) receptor antagonist chlorpheniramine., Hong HK., Korean J Physiol Pharmacol. June 1, 2009; 13 (3): 215-20.


Two separate interfaces between the voltage sensor and pore are required for the function of voltage-dependent K(+) channels., Lee SY., PLoS Biol. March 3, 2009; 7 (3): e47.              


Discovery of a novel activator of KCNQ1-KCNE1 K channel complexes., Mruk K., PLoS One. January 1, 2009; 4 (1): e4236.          


Papaverine, a vasodilator, blocks the pore of the HERG channel at submicromolar concentration., Kim YJ., J Cardiovasc Pharmacol. December 1, 2008; 52 (6): 485-93.


A new C-terminal hERG mutation A915fs+47X associated with symptomatic LQT2 and auditory-trigger syncope., Christé G., Heart Rhythm. November 1, 2008; 5 (11): 1577-86.


[Analysis and analyzing mechanisms of HERG channel kinetics]., Wang X., Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. October 1, 2008; 25 (5): 1068-73.


Clomipramine block of the hERG K+ channel: accessibility to F656 and Y652., Jo SH., Eur J Pharmacol. September 11, 2008; 592 (1-3): 19-25.


Blockade of the human ether-a-go-go-related gene potassium channel by ketanserin., Tu DN., Sheng Li Xue Bao. August 25, 2008; 60 (4): 525-34.


An extracellular Cu2+ binding site in the voltage sensor of BK and Shaker potassium channels., Ma Z., J Gen Physiol. May 1, 2008; 131 (5): 483-502.                      


Protriptyline block of the human ether-à-go-go-related gene (HERG) K+ channel., Jo SH., Life Sci. January 30, 2008; 82 (5-6): 331-40.


Biophysical characterization of the short QT mutation hERG-N588K reveals a mixed gain-and loss-of-function., Grunnet M., Cell Physiol Biochem. January 1, 2008; 22 (5-6): 611-24.


Maprotiline block of the human ether-a-go-go-related gene (HERG) K+ channel., Jo SH., Arch Pharm Res. April 1, 2007; 30 (4): 453-60.


Structural requirements of human ether-a-go-go-related gene channels for block by bupivacaine., Siebrands CC., Anesthesiology. March 1, 2007; 106 (3): 523-31.


Blockade of HERG human K+ channel and IKr of guinea pig cardiomyocytes by prochlorperazine., Kim MD., Eur J Pharmacol. August 21, 2006; 544 (1-3): 82-90.


In vitro modulation of HERG channels by organochlorine solvent trichlormethane as potential explanation for proarrhythmic effects of chloroform., Scholz EP., Toxicol Lett. August 20, 2006; 165 (2): 156-66.


Blockade of HERG human K+ channels and IKr of guinea-pig cardiomyocytes by the antipsychotic drug clozapine., Lee SY., Br J Pharmacol. June 1, 2006; 148 (4): 499-509.


Chemical modification of the human ether-a-go-go-related gene (HERG) K+ current by the amino-group reagent trinitrobenzene sulfonic acid., Jo SH., Arch Pharm Res. April 1, 2006; 29 (4): 310-7.


The effects of sevoflurane and propofol on QT interval and heterologously expressed human ether-a-go-go related gene currents in Xenopus oocytes., Yamada M., Anesth Analg. January 1, 2006; 102 (1): 98-103.


Activation of human ether-a-go-go-related gene potassium channels by the diphenylurea 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643)., Hansen RS., Mol Pharmacol. January 1, 2006; 69 (1): 266-77.


Expression and functional characterization of the human ether-à-go-go-related gene (HERG) K+ channel cardiac splice variant in Xenopus laevis oocytes., Aydar E., J Membr Biol. January 1, 2006; 211 (2): 115-26.


Inhibitory effect of rhynchophylline on human ether-a-go-go related gene channel., Gui L., Sheng Li Xue Bao. October 25, 2005; 57 (5): 648-52.


Inhibition of human ether-a-go-go-related gene K+ channel and IKr of guinea pig cardiomyocytes by antipsychotic drug trifluoperazine., Choi SY., J Pharmacol Exp Ther. May 1, 2005; 313 (2): 888-95.


The influence of extracellular acidosis on the effect of IKr blockers., Lin C., J Cardiovasc Pharmacol Ther. March 1, 2005; 10 (1): 67-76.


A mechanism for the potential proarrhythmic effect of acidosis, bradycardia, and hypokalemia on the blockade of human ether-a-go-go-related gene (HERG) channels., Lin C., Am J Ther. January 1, 2005; 12 (4): 328-36.


Salt bridges and gating in the COOH-terminal region of HCN2 and CNGA1 channels., Craven KB., J Gen Physiol. December 1, 2004; 124 (6): 663-77.                      


Gating charges in the activation and inactivation processes of the HERG channel., Zhang M., J Gen Physiol. December 1, 2004; 124 (6): 703-18.                    


Effects of the atrial antiarrhythmic drug AVE0118 on cardiac ion channels., Gögelein H., Naunyn Schmiedebergs Arch Pharmacol. September 1, 2004; 370 (3): 183-92.


Probucol aggravates long QT syndrome associated with a novel missense mutation M124T in the N-terminus of HERG., Hayashi K., Clin Sci (Lond). August 1, 2004; 107 (2): 175-82.


Molecular determinants for high-affinity block of human EAG potassium channels by antiarrhythmic agents., Gessner G., Mol Pharmacol. May 1, 2004; 65 (5): 1120-9.


Block of HERG human K(+) channel and IKr of guinea pig cardiomyocytes by chlorpromazine., Lee SY., J Cardiovasc Pharmacol. May 1, 2004; 43 (5): 706-14.


Acute effects of dronedarone on both components of the cardiac delayed rectifier K+ current, HERG and KvLQT1/minK potassium channels., Thomas D., Br J Pharmacol. November 1, 2003; 140 (5): 996-1002.


Negative charges in the transmembrane domains of the HERG K channel are involved in the activation- and deactivation-gating processes., Liu J., J Gen Physiol. June 1, 2003; 121 (6): 599-614.                                  


[K(+)](o)-dependent change in conformation of the HERG1 long QT mutation N629D channel results in partial reversal of the in vitro disease phenotype., Teng GQ., Cardiovasc Res. March 1, 2003; 57 (3): 642-50.


Structural and functional role of the extracellular s5-p linker in the HERG potassium channel., Liu J., J Gen Physiol. November 1, 2002; 120 (5): 723-37.                  


Fenamate-induced enhancement of heterologously expressed HERG currents in Xenopus oocytes., Malykhina AP., Eur J Pharmacol. October 11, 2002; 452 (3): 269-77.


Kinetic modulation of HERG potassium channels by the volatile anesthetic halothane., Li J., Anesthesiology. October 1, 2002; 97 (4): 921-30.


Bertosamil blocks HERG potassium channels in their open and inactivated states., Zitron E., Br J Pharmacol. September 1, 2002; 137 (2): 221-8.


Open channel block by KCB-328 [1-(2-amino-4-methanesulfonamidophenoxy)-2-[N-(3,4-dimethoxyphenethyl)-N-methylamino]ethane hydrochloride] of the heterologously expressed human ether-a-go-go-related gene K+ channels., Park JB., J Pharmacol Exp Ther. July 1, 2002; 302 (1): 314-9.


Protein kinase A-mediated phosphorylation of HERG potassium channels in a human cell line., Wei Z., Chin Med J (Engl). May 1, 2002; 115 (5): 668-76.


Characterization of a novel missense mutation E637K in the pore-S6 loop of HERG in a patient with long QT syndrome., Hayashi K., Cardiovasc Res. April 1, 2002; 54 (1): 67-76.


Fast and slow voltage sensor movements in HERG potassium channels., Smith PL., J Gen Physiol. March 1, 2002; 119 (3): 275-93.                        


Blocking effects of the antiarrhythmic drug propafenone on the HERG potassium channel., Mergenthaler J., Naunyn Schmiedebergs Arch Pharmacol. April 1, 2001; 363 (4): 472-80.

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