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High affinity open channel block by dofetilide of HERG expressed in a human cell line. , Snyders DJ., Mol Pharmacol. June 1, 1996; 49 (6): 949-55.
Blockade of HERG channels by the class III antiarrhythmic azimilide: mode of action. , Busch AE., Br J Pharmacol. January 1, 1998; 123 (1): 23-30.
Modulation of human erg K+ channel gating by activation of a G protein-coupled receptor and protein kinase C. , Barros F., J Physiol. September 1, 1998; 511 ( Pt 2) 333-46.
Regulation of deactivation by an amino terminal domain in human ether-à- go-go-related gene potassium channels. , Wang J ., J Gen Physiol. November 1, 1998; 112 (5): 637-47.
Inhibitory effects of the class III antiarrhythmic drug amiodarone on cloned HERG potassium channels. , Kiehn J., Naunyn Schmiedebergs Arch Pharmacol. March 1, 1999; 359 (3): 212-9.
Proton and zinc effects on HERG currents. , Anumonwo JM., Biophys J. July 1, 1999; 77 (1): 282-98.
Trapping of a methanesulfonanilide by closure of the HERG potassium channel activation gate. , Mitcheson JS., J Gen Physiol. March 1, 2000; 115 (3): 229-40.
Novel gain-of-function mechanism in K(+) channel-related long-QT syndrome: altered gating and selectivity in the HERG1 N629D mutant. , Lees-Miller JP., Circ Res. March 17, 2000; 86 (5): 507-13.
Blockade of the HERG human cardiac K(+) channel by the antidepressant drug amitriptyline. , Jo SH., Br J Pharmacol. April 1, 2000; 129 (7): 1474-80.
Dynamic control of deactivation gating by a soluble amino-terminal domain in HERG K(+) channels. , Wang J ., J Gen Physiol. June 1, 2000; 115 (6): 749-58.
MinK subdomains that mediate modulation of and association with KvLQT1. , Tapper AR., J Gen Physiol. September 1, 2000; 116 (3): 379-90.
Antiarrhythmic drug carvedilol inhibits HERG potassium channels. , Karle CA., Cardiovasc Res. February 1, 2001; 49 (2): 361-70.
Blocking effects of the antiarrhythmic drug propafenone on the HERG potassium channel. , Mergenthaler J., Naunyn Schmiedebergs Arch Pharmacol. April 1, 2001; 363 (4): 472-80.
Fast and slow voltage sensor movements in HERG potassium channels. , Smith PL., J Gen Physiol. March 1, 2002; 119 (3): 275-93.
Characterization of a novel missense mutation E637K in the pore-S6 loop of HERG in a patient with long QT syndrome. , Hayashi K., Cardiovasc Res. April 1, 2002; 54 (1): 67-76.
Protein kinase A-mediated phosphorylation of HERG potassium channels in a human cell line. , Wei Z., Chin Med J (Engl). May 1, 2002; 115 (5): 668-76.
Open channel block by KCB-328 [1-(2-amino-4-methanesulfonamidophenoxy)-2-[N-(3,4-dimethoxyphenethyl)-N-methylamino]ethane hydrochloride] of the heterologously expressed human ether-a- go-go-related gene K+ channels. , Park JB ., J Pharmacol Exp Ther. July 1, 2002; 302 (1): 314-9.
Bertosamil blocks HERG potassium channels in their open and inactivated states. , Zitron E., Br J Pharmacol. September 1, 2002; 137 (2): 221-8.
Kinetic modulation of HERG potassium channels by the volatile anesthetic halothane. , Li J., Anesthesiology. October 1, 2002; 97 (4): 921-30.
Fenamate-induced enhancement of heterologously expressed HERG currents in Xenopus oocytes. , Malykhina AP., Eur J Pharmacol. October 11, 2002; 452 (3): 269-77.
Structural and functional role of the extracellular s5-p linker in the HERG potassium channel. , Liu J ., J Gen Physiol. November 1, 2002; 120 (5): 723-37.
[K(+)](o)-dependent change in conformation of the HERG1 long QT mutation N629D channel results in partial reversal of the in vitro disease phenotype. , Teng GQ., Cardiovasc Res. March 1, 2003; 57 (3): 642-50.
Negative charges in the transmembrane domains of the HERG K channel are involved in the activation- and deactivation-gating processes. , Liu J ., J Gen Physiol. June 1, 2003; 121 (6): 599-614.
Acute effects of dronedarone on both components of the cardiac delayed rectifier K+ current, HERG and KvLQT1/ minK potassium channels. , Thomas D., Br J Pharmacol. November 1, 2003; 140 (5): 996-1002.
Molecular determinants for high-affinity block of human EAG potassium channels by antiarrhythmic agents. , Gessner G., Mol Pharmacol. May 1, 2004; 65 (5): 1120-9.
Block of HERG human K(+) channel and IKr of guinea pig cardiomyocytes by chlorpromazine. , Lee SY., J Cardiovasc Pharmacol. May 1, 2004; 43 (5): 706-14.
Probucol aggravates long QT syndrome associated with a novel missense mutation M124T in the N-terminus of HERG. , Hayashi K., Clin Sci (Lond). August 1, 2004; 107 (2): 175-82.
Effects of the atrial antiarrhythmic drug AVE0118 on cardiac ion channels. , Gögelein H., Naunyn Schmiedebergs Arch Pharmacol. September 1, 2004; 370 (3): 183-92.
Salt bridges and gating in the COOH-terminal region of HCN2 and CNGA1 channels. , Craven KB., J Gen Physiol. December 1, 2004; 124 (6): 663-77.
Gating charges in the activation and inactivation processes of the HERG channel. , Zhang M., J Gen Physiol. December 1, 2004; 124 (6): 703-18.
A mechanism for the potential proarrhythmic effect of acidosis, bradycardia, and hypokalemia on the blockade of human ether-a- go-go-related gene ( HERG) channels. , Lin C., Am J Ther. January 1, 2005; 12 (4): 328-36.
The influence of extracellular acidosis on the effect of IKr blockers. , Lin C., J Cardiovasc Pharmacol Ther. March 1, 2005; 10 (1): 67-76.
Inhibition of human ether-a- go-go-related gene K+ channel and IKr of guinea pig cardiomyocytes by antipsychotic drug trifluoperazine. , Choi SY., J Pharmacol Exp Ther. May 1, 2005; 313 (2): 888-95.
Inhibitory effect of rhynchophylline on human ether-a- go-go related gene channel. , Gui L., Sheng Li Xue Bao. October 25, 2005; 57 (5): 648-52.
The effects of sevoflurane and propofol on QT interval and heterologously expressed human ether-a- go-go related gene currents in Xenopus oocytes. , Yamada M., Anesth Analg. January 1, 2006; 102 (1): 98-103.
Activation of human ether-a- go-go-related gene potassium channels by the diphenylurea 1,3- bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643). , Hansen RS., Mol Pharmacol. January 1, 2006; 69 (1): 266-77.
Expression and functional characterization of the human ether-à- go-go-related gene ( HERG) K+ channel cardiac splice variant in Xenopus laevis oocytes. , Aydar E., J Membr Biol. January 1, 2006; 211 (2): 115-26.
Chemical modification of the human ether-a- go-go-related gene ( HERG) K+ current by the amino-group reagent trinitrobenzene sulfonic acid. , Jo SH., Arch Pharm Res. April 1, 2006; 29 (4): 310-7.
Blockade of HERG human K+ channels and IKr of guinea-pig cardiomyocytes by the antipsychotic drug clozapine. , Lee SY., Br J Pharmacol. June 1, 2006; 148 (4): 499-509.
In vitro modulation of HERG channels by organochlorine solvent trichlormethane as potential explanation for proarrhythmic effects of chloroform. , Scholz EP., Toxicol Lett. August 20, 2006; 165 (2): 156-66.
Blockade of HERG human K+ channel and IKr of guinea pig cardiomyocytes by prochlorperazine. , Kim MD ., Eur J Pharmacol. August 21, 2006; 544 (1-3): 82-90.
Structural requirements of human ether-a- go-go-related gene channels for block by bupivacaine. , Siebrands CC., Anesthesiology. March 1, 2007; 106 (3): 523-31.
Maprotiline block of the human ether-a- go-go-related gene ( HERG) K+ channel. , Jo SH., Arch Pharm Res. April 1, 2007; 30 (4): 453-60.
Biophysical characterization of the short QT mutation hERG-N588K reveals a mixed gain-and loss-of-function. , Grunnet M., Cell Physiol Biochem. January 1, 2008; 22 (5-6): 611-24.
Protriptyline block of the human ether-à- go-go-related gene ( HERG) K+ channel. , Jo SH., Life Sci. January 30, 2008; 82 (5-6): 331-40.
An extracellular Cu2+ binding site in the voltage sensor of BK and Shaker potassium channels. , Ma Z., J Gen Physiol. May 1, 2008; 131 (5): 483-502.
Blockade of the human ether-a- go-go-related gene potassium channel by ketanserin. , Tu DN., Sheng Li Xue Bao. August 25, 2008; 60 (4): 525-34.
Clomipramine block of the hERG K+ channel: accessibility to F656 and Y652. , Jo SH., Eur J Pharmacol. September 11, 2008; 592 (1-3): 19-25.
[Analysis and analyzing mechanisms of HERG channel kinetics]. , Wang X ., Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. October 1, 2008; 25 (5): 1068-73.
A new C-terminal hERG mutation A915fs+47X associated with symptomatic LQT2 and auditory-trigger syncope. , Christé G., Heart Rhythm. November 1, 2008; 5 (11): 1577-86.