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Summary Anatomy Item Literature (4079) Expression Attributions Wiki
XB-ANAT-86

Papers associated with tail region (and kcnh2)

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High affinity open channel block by dofetilide of HERG expressed in a human cell line., Snyders DJ., Mol Pharmacol. June 1, 1996; 49 (6): 949-55.


Blockade of HERG channels by the class III antiarrhythmic azimilide: mode of action., Busch AE., Br J Pharmacol. January 1, 1998; 123 (1): 23-30.


Modulation of human erg K+ channel gating by activation of a G protein-coupled receptor and protein kinase C., Barros F., J Physiol. September 1, 1998; 511 ( Pt 2) 333-46.


Regulation of deactivation by an amino terminal domain in human ether-à-go-go-related gene potassium channels., Wang J., J Gen Physiol. November 1, 1998; 112 (5): 637-47.              


Inhibitory effects of the class III antiarrhythmic drug amiodarone on cloned HERG potassium channels., Kiehn J., Naunyn Schmiedebergs Arch Pharmacol. March 1, 1999; 359 (3): 212-9.


Proton and zinc effects on HERG currents., Anumonwo JM., Biophys J. July 1, 1999; 77 (1): 282-98.


Trapping of a methanesulfonanilide by closure of the HERG potassium channel activation gate., Mitcheson JS., J Gen Physiol. March 1, 2000; 115 (3): 229-40.                    


Novel gain-of-function mechanism in K(+) channel-related long-QT syndrome: altered gating and selectivity in the HERG1 N629D mutant., Lees-Miller JP., Circ Res. March 17, 2000; 86 (5): 507-13.


Blockade of the HERG human cardiac K(+) channel by the antidepressant drug amitriptyline., Jo SH., Br J Pharmacol. April 1, 2000; 129 (7): 1474-80.


Dynamic control of deactivation gating by a soluble amino-terminal domain in HERG K(+) channels., Wang J., J Gen Physiol. June 1, 2000; 115 (6): 749-58.              


MinK subdomains that mediate modulation of and association with KvLQT1., Tapper AR., J Gen Physiol. September 1, 2000; 116 (3): 379-90.          


Antiarrhythmic drug carvedilol inhibits HERG potassium channels., Karle CA., Cardiovasc Res. February 1, 2001; 49 (2): 361-70.


Blocking effects of the antiarrhythmic drug propafenone on the HERG potassium channel., Mergenthaler J., Naunyn Schmiedebergs Arch Pharmacol. April 1, 2001; 363 (4): 472-80.


Fast and slow voltage sensor movements in HERG potassium channels., Smith PL., J Gen Physiol. March 1, 2002; 119 (3): 275-93.                        


Characterization of a novel missense mutation E637K in the pore-S6 loop of HERG in a patient with long QT syndrome., Hayashi K., Cardiovasc Res. April 1, 2002; 54 (1): 67-76.


Protein kinase A-mediated phosphorylation of HERG potassium channels in a human cell line., Wei Z., Chin Med J (Engl). May 1, 2002; 115 (5): 668-76.


Open channel block by KCB-328 [1-(2-amino-4-methanesulfonamidophenoxy)-2-[N-(3,4-dimethoxyphenethyl)-N-methylamino]ethane hydrochloride] of the heterologously expressed human ether-a-go-go-related gene K+ channels., Park JB., J Pharmacol Exp Ther. July 1, 2002; 302 (1): 314-9.


Bertosamil blocks HERG potassium channels in their open and inactivated states., Zitron E., Br J Pharmacol. September 1, 2002; 137 (2): 221-8.


Kinetic modulation of HERG potassium channels by the volatile anesthetic halothane., Li J., Anesthesiology. October 1, 2002; 97 (4): 921-30.


Fenamate-induced enhancement of heterologously expressed HERG currents in Xenopus oocytes., Malykhina AP., Eur J Pharmacol. October 11, 2002; 452 (3): 269-77.


Structural and functional role of the extracellular s5-p linker in the HERG potassium channel., Liu J., J Gen Physiol. November 1, 2002; 120 (5): 723-37.                  


[K(+)](o)-dependent change in conformation of the HERG1 long QT mutation N629D channel results in partial reversal of the in vitro disease phenotype., Teng GQ., Cardiovasc Res. March 1, 2003; 57 (3): 642-50.


Negative charges in the transmembrane domains of the HERG K channel are involved in the activation- and deactivation-gating processes., Liu J., J Gen Physiol. June 1, 2003; 121 (6): 599-614.                                  


Acute effects of dronedarone on both components of the cardiac delayed rectifier K+ current, HERG and KvLQT1/minK potassium channels., Thomas D., Br J Pharmacol. November 1, 2003; 140 (5): 996-1002.


Molecular determinants for high-affinity block of human EAG potassium channels by antiarrhythmic agents., Gessner G., Mol Pharmacol. May 1, 2004; 65 (5): 1120-9.


Block of HERG human K(+) channel and IKr of guinea pig cardiomyocytes by chlorpromazine., Lee SY., J Cardiovasc Pharmacol. May 1, 2004; 43 (5): 706-14.


Probucol aggravates long QT syndrome associated with a novel missense mutation M124T in the N-terminus of HERG., Hayashi K., Clin Sci (Lond). August 1, 2004; 107 (2): 175-82.


Effects of the atrial antiarrhythmic drug AVE0118 on cardiac ion channels., Gögelein H., Naunyn Schmiedebergs Arch Pharmacol. September 1, 2004; 370 (3): 183-92.


Salt bridges and gating in the COOH-terminal region of HCN2 and CNGA1 channels., Craven KB., J Gen Physiol. December 1, 2004; 124 (6): 663-77.                      


Gating charges in the activation and inactivation processes of the HERG channel., Zhang M., J Gen Physiol. December 1, 2004; 124 (6): 703-18.                    


A mechanism for the potential proarrhythmic effect of acidosis, bradycardia, and hypokalemia on the blockade of human ether-a-go-go-related gene (HERG) channels., Lin C., Am J Ther. January 1, 2005; 12 (4): 328-36.


The influence of extracellular acidosis on the effect of IKr blockers., Lin C., J Cardiovasc Pharmacol Ther. March 1, 2005; 10 (1): 67-76.


Inhibition of human ether-a-go-go-related gene K+ channel and IKr of guinea pig cardiomyocytes by antipsychotic drug trifluoperazine., Choi SY., J Pharmacol Exp Ther. May 1, 2005; 313 (2): 888-95.


Inhibitory effect of rhynchophylline on human ether-a-go-go related gene channel., Gui L., Sheng Li Xue Bao. October 25, 2005; 57 (5): 648-52.


The effects of sevoflurane and propofol on QT interval and heterologously expressed human ether-a-go-go related gene currents in Xenopus oocytes., Yamada M., Anesth Analg. January 1, 2006; 102 (1): 98-103.


Activation of human ether-a-go-go-related gene potassium channels by the diphenylurea 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643)., Hansen RS., Mol Pharmacol. January 1, 2006; 69 (1): 266-77.


Expression and functional characterization of the human ether-à-go-go-related gene (HERG) K+ channel cardiac splice variant in Xenopus laevis oocytes., Aydar E., J Membr Biol. January 1, 2006; 211 (2): 115-26.


Chemical modification of the human ether-a-go-go-related gene (HERG) K+ current by the amino-group reagent trinitrobenzene sulfonic acid., Jo SH., Arch Pharm Res. April 1, 2006; 29 (4): 310-7.


Blockade of HERG human K+ channels and IKr of guinea-pig cardiomyocytes by the antipsychotic drug clozapine., Lee SY., Br J Pharmacol. June 1, 2006; 148 (4): 499-509.


In vitro modulation of HERG channels by organochlorine solvent trichlormethane as potential explanation for proarrhythmic effects of chloroform., Scholz EP., Toxicol Lett. August 20, 2006; 165 (2): 156-66.


Blockade of HERG human K+ channel and IKr of guinea pig cardiomyocytes by prochlorperazine., Kim MD., Eur J Pharmacol. August 21, 2006; 544 (1-3): 82-90.


Structural requirements of human ether-a-go-go-related gene channels for block by bupivacaine., Siebrands CC., Anesthesiology. March 1, 2007; 106 (3): 523-31.


Maprotiline block of the human ether-a-go-go-related gene (HERG) K+ channel., Jo SH., Arch Pharm Res. April 1, 2007; 30 (4): 453-60.


Biophysical characterization of the short QT mutation hERG-N588K reveals a mixed gain-and loss-of-function., Grunnet M., Cell Physiol Biochem. January 1, 2008; 22 (5-6): 611-24.


Protriptyline block of the human ether-à-go-go-related gene (HERG) K+ channel., Jo SH., Life Sci. January 30, 2008; 82 (5-6): 331-40.


An extracellular Cu2+ binding site in the voltage sensor of BK and Shaker potassium channels., Ma Z., J Gen Physiol. May 1, 2008; 131 (5): 483-502.                      


Blockade of the human ether-a-go-go-related gene potassium channel by ketanserin., Tu DN., Sheng Li Xue Bao. August 25, 2008; 60 (4): 525-34.


Clomipramine block of the hERG K+ channel: accessibility to F656 and Y652., Jo SH., Eur J Pharmacol. September 11, 2008; 592 (1-3): 19-25.


[Analysis and analyzing mechanisms of HERG channel kinetics]., Wang X., Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. October 1, 2008; 25 (5): 1068-73.


A new C-terminal hERG mutation A915fs+47X associated with symptomatic LQT2 and auditory-trigger syncope., Christé G., Heart Rhythm. November 1, 2008; 5 (11): 1577-86.

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