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Membrane potential drives the exit from pluripotency and cell fate commitment via calcium and mTOR. , Sempou E., Nat Commun. November 5, 2022; 13 (1): 6681.
Mutations in the voltage-gated potassium channel gene KCNH1 cause Temple-Baraitser syndrome and epilepsy. , Simons C., Nat Genet. January 1, 2015; 47 (1): 73-7.
Kcnh1 voltage-gated potassium channels are essential for early zebrafish development. , Stengel R., J Biol Chem. October 12, 2012; 287 (42): 35565-35575.
Marine algal toxin azaspiracid is an open-state blocker of hERG potassium channels. , Twiner MJ., Chem Res Toxicol. September 17, 2012; 25 (9): 1975-84.
Probing the binding sites and mechanisms of action of two human ether-a- go-go-related gene channel activators, 1,3- bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643) and 2-[2-(3,4-dichloro-phenyl)-2,3-dihydro-1H-isoindol-5-ylamino]-nicotinic acid (PD307243). , Xu X., Mol Pharmacol. June 1, 2008; 73 (6): 1709-21.
Effect of S5P alpha-helix charge mutants on inactivation of hERG K+ channels. , Clarke CE., J Physiol. June 1, 2006; 573 (Pt 2): 291-304.
Gating charges in the activation and inactivation processes of the HERG channel. , Zhang M., J Gen Physiol. December 1, 2004; 124 (6): 703-18.
Molecular determinants for activation and inactivation of HERG, a human inward rectifier potassium channel. , Schönherr R., J Physiol. June 15, 1996; 493 ( Pt 3) 635-42.