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Summary Anatomy Item Literature (6278) Expression Attributions Wiki
XB-ANAT-475

Papers associated with primary germ layer (and lrp6)

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R-Spondin 2 governs Xenopus left-right body axis formation by establishing an FGF signaling gradient., Lee H, Lee H., Nat Commun. February 2, 2024; 15 (1): 1003.                                                                  

The early dorsal signal in vertebrate embryos requires endolysosomal membrane trafficking., Azbazdar Y., Bioessays. January 1, 2024; 46 (1): e2300179.                            

Maternal Wnt11b regulates cortical rotation during Xenopus axis formation: analysis of maternal-effect wnt11b mutants., Houston DW., Development. September 1, 2022; 149 (17):                                   

Lysosomes are required for early dorsal signaling in the Xenopus embryo., Tejeda-Muñoz N., Proc Natl Acad Sci U S A. April 26, 2022; 119 (17): e2201008119.                          

Wnt-inducible Lrp6-APEX2 interacting proteins identify ESCRT machinery and Trk-fused gene as components of the Wnt signaling pathway., Colozza G., Sci Rep. December 9, 2020; 10 (1): 21555.            

TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis., Chen M., Elife. September 14, 2020; 9                                                                                           

Bighead is a Wnt antagonist secreted by the Xenopus Spemann organizer that promotes Lrp6 endocytosis., Ding Y., Proc Natl Acad Sci U S A. September 25, 2018; 115 (39): E9135-E9144.                    

Dkk2 promotes neural crest specification by activating Wnt/β-catenin signaling in a GSK3β independent manner., Devotta A., Elife. July 23, 2018; 7                             

Roles of two types of heparan sulfate clusters in Wnt distribution and signaling in Xenopus., Mii Y., Nat Commun. December 7, 2017; 8 (1): 1973.                                                  

Angiopoietin-like 4 Is a Wnt Signaling Antagonist that Promotes LRP6 Turnover., Kirsch N., Dev Cell. October 9, 2017; 43 (1): 71-82.e6.                                

The phosphatase Pgam5 antagonizes Wnt/β-Catenin signaling in embryonic anterior-posterior axis patterning., Rauschenberger V., Development. June 15, 2017; 144 (12): 2234-2247.                                      

Ubiquitin C-terminal hydrolase37 regulates Tcf7 DNA binding for the activation of Wnt signalling., Han W., Sci Rep. February 15, 2017; 7 42590.                        

Apolipoprotein C-I mediates Wnt/Ctnnb1 signaling during neural border formation and is required for neural crest development., Yokota C., Int J Dev Biol. January 1, 2017; 61 (6-7): 415-425.                      

Notum is required for neural and head induction via Wnt deacylation, oxidation, and inactivation., Zhang X., Dev Cell. March 23, 2015; 32 (6): 719-30.                                  

A Molecular atlas of Xenopus respiratory system development., Rankin SA, Rankin SA., Dev Dyn. January 1, 2015; 244 (1): 69-85.                    

Isoquercitrin suppresses colon cancer cell growth in vitro by targeting the Wnt/β-catenin signaling pathway., Amado NG., J Biol Chem. December 19, 2014; 289 (51): 35456-67.                  

Cholesterol selectively activates canonical Wnt signalling over non-canonical Wnt signalling., Sheng R., Nat Commun. July 15, 2014; 5 4393.              

Polarized Wnt signaling regulates ectodermal cell fate in Xenopus., Huang YL., Dev Cell. April 28, 2014; 29 (2): 250-7.                  

RAB8B is required for activity and caveolar endocytosis of LRP6., Demir K., Cell Rep. September 26, 2013; 4 (6): 1224-34.                    

Lypd6 enhances Wnt/β-catenin signaling by promoting Lrp6 phosphorylation in raft plasma membrane domains., Özhan G., Dev Cell. August 26, 2013; 26 (4): 331-45.

The Xenopus Tgfbi is required for embryogenesis through regulation of canonical Wnt signalling., Wang F., Dev Biol. July 1, 2013; 379 (1): 16-27.                            

Role of the Rap2/TNIK kinase pathway in regulation of LRP6 stability for Wnt signaling., Park DS., Biochem Biophys Res Commun. June 28, 2013; 436 (2): 338-43.        

Essential role of AWP1 in neural crest specification in Xenopus., Seo JH., Int J Dev Biol. January 1, 2013; 57 (11-12): 829-36.                  

Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation., Zhang X., Cell. June 22, 2012; 149 (7): 1565-77.                      

Maternal xNorrin, a canonical Wnt signaling agonist and TGF-β antagonist, controls early neuroectoderm specification in Xenopus., Xu S., PLoS Biol. January 1, 2012; 10 (3): e1001286.                                    

Waif1/5T4 inhibits Wnt/β-catenin signaling and activates noncanonical Wnt pathways by modifying LRP6 subcellular localization., Kagermeier-Schenk B., Dev Cell. December 13, 2011; 21 (6): 1129-43.        

Transmembrane protein 198 promotes LRP6 phosphorylation and Wnt signaling activation., Liang J., Mol Cell Biol. July 1, 2011; 31 (13): 2577-90.

Phosphorylation of TCF proteins by homeodomain-interacting protein kinase 2., Hikasa H., J Biol Chem. April 8, 2011; 286 (14): 12093-100.

Transdifferentiation from cornea to lens in Xenopus laevis depends on BMP signalling and involves upregulation of Wnt signalling., Day RC., BMC Dev Biol. January 26, 2011; 11 54.                                                

Extracellular regulation of developmental cell signaling by XtSulf1., Freeman SD., Dev Biol. August 15, 2008; 320 (2): 436-45.            

Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal., Fuentealba LC., Cell. November 30, 2007; 131 (5): 980-93.      

Wise retained in the endoplasmic reticulum inhibits Wnt signaling by reducing cell surface LRP6., Guidato S., Dev Biol. October 15, 2007; 310 (2): 250-63.                

Mouse homologues of Shisa antagonistic to Wnt and Fgf signalings., Furushima K., Dev Biol. June 15, 2007; 306 (2): 480-92.  

Wnt11/beta-catenin signaling in both oocytes and early embryos acts through LRP6-mediated regulation of axin., Kofron M., Development. February 1, 2007; 134 (3): 503-13.      

Shisa2 promotes the maturation of somitic precursors and transition to the segmental fate in Xenopus embryos., Nagano T., Development. December 1, 2006; 133 (23): 4643-54.                  

The MRH protein Erlectin is a member of the endoplasmic reticulum synexpression group and functions in N-glycan recognition., Cruciat CM., J Biol Chem. May 5, 2006; 281 (18): 12986-93.                        

Early steps in neural crest specification., Barembaum M., Semin Cell Dev Biol. December 1, 2005; 16 (6): 642-6.      

Xenopus frizzled-4S, a splicing variant of Xfz4 is a context-dependent activator and inhibitor of Wnt/beta-catenin signaling., Swain RK., Cell Commun Signal. October 19, 2005; 3 12.          

Shisa promotes head formation through the inhibition of receptor protein maturation for the caudalizing factors, Wnt and FGF., Yamamoto A., Cell. January 28, 2005; 120 (2): 223-35.                      

Connective-tissue growth factor modulates WNT signalling and interacts with the WNT receptor complex., Mercurio S., Development. May 1, 2004; 131 (9): 2137-47.                    

Wise, a context-dependent activator and inhibitor of Wnt signalling., Itasaki N., Development. September 1, 2003; 130 (18): 4295-305.                

Kremen proteins interact with Dickkopf1 to regulate anteroposterior CNS patterning., Davidson G., Development. December 1, 2002; 129 (24): 5587-96.        

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