Papers associated with vestibule

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	A ring of threonines in the inner vestibule of the pore of CNGA1 channels constitutes a binding site for permeating ions., Marchesi A., J Physiol. October 15, 2012; 590 (20): 5075-90.
	High Ca(2+) permeability of a peptide-gated DEG/ENaC from Hydra., Dürrnagel S., J Gen Physiol. October 1, 2012; 140 (4): 391-402.
	Characterization of a novel somatic KCNJ5 mutation delI157 in an aldosterone-producing adenoma., Murthy M., J Hypertens. September 1, 2012; 30 (9): 1827-33.
	Localization of a site of action for benzofuroindole-induced potentiation of BKCa channels., Lee BC., Mol Pharmacol. August 1, 2012; 82 (2): 143-55.
	Bridging the gap between structure and kinetics of human SGLT1., Sala-Rabanal M., Am J Physiol Cell Physiol. May 1, 2012; 302 (9): C1293-305.
	Contribution of residues in second transmembrane domain of ASIC1a protein to ion selectivity., Carattino MD., J Biol Chem. April 13, 2012; 287 (16): 12927-34.
	Agonist binding evokes extensive conformational changes in the extracellular domain of the ATP-gated human P2X1 receptor ion channel., Roberts JA., Proc Natl Acad Sci U S A. March 20, 2012; 109 (12): 4663-7.
	Cystic fibrosis transmembrane conductance regulator: a molecular model defines the architecture of the anion conduction path and locates a "bottleneck" in the pore., Norimatsu Y., Biochemistry. March 20, 2012; 51 (11): 2199-212.
	An aspartate residue in the external vestibule of GLYT2 (glycine transporter 2) controls cation access and transport coupling., Pérez-Siles G., Biochem J. March 1, 2012; 442 (2): 323-34.
	Mechanism of inhibition of connexin channels by the quinine derivative N-benzylquininium., Rubinos C., J Gen Physiol. January 1, 2012; 139 (1): 69-82.
	5-HT3 receptor ion size selectivity is a property of the transmembrane channel, not the cytoplasmic vestibule portals., McKinnon NK., J Gen Physiol. October 1, 2011; 138 (4): 453-66.
	Cysteine scanning mutagenesis (residues Glu52-Gly96) of the human P2X1 receptor for ATP: mapping agonist binding and channel gating., Allsopp RC., J Biol Chem. August 19, 2011; 286 (33): 29207-17.
	Contributions of counter-charge in a potassium channel voltage-sensor domain., Pless SA., Nat Chem Biol. July 24, 2011; 7 (9): 617-23.
	Episodic ataxia type 1 mutations affect fast inactivation of K+ channels by a reduction in either subunit surface expression or affinity for inactivation domain., Imbrici P., Am J Physiol Cell Physiol. June 1, 2011; 300 (6): C1314-22.
	Aversion to nicotine is regulated by the balanced activity of β4 and α5 nicotinic receptor subunits in the medial habenula., Frahm S., Neuron. May 12, 2011; 70 (3): 522-35.
	Insights into the mechanism of pore opening of acid-sensing ion channel 1a., Tolino LA., J Biol Chem. May 6, 2011; 286 (18): 16297-307.
	In glycine and GABA(A) channels, different subunits contribute asymmetrically to channel conductance via residues in the extracellular domain., Moroni M., J Biol Chem. April 15, 2011; 286 (15): 13414-22.
	Role of an extracellular loop in determining the stoichiometry of Na+-HCO₃⁻ cotransporters., Chen LM., J Physiol. February 15, 2011; 589 (Pt 4): 877-90.
	Asymmetric configurations and N-terminal rearrangements in connexin26 gap junction channels., Oshima A., J Mol Biol. January 21, 2011; 405 (3): 724-35.
	A molecular switch between the outer and the inner vestibules of the voltage-gated Na+ channel., Zarrabi T., J Biol Chem. December 10, 2010; 285 (50): 39458-70.
	A pore residue of the KCNQ3 potassium M-channel subunit controls surface expression., Gómez-Posada JC., J Neurosci. July 7, 2010; 30 (27): 9316-23.
	Cooccupancy of the outer vestibule of voltage-gated sodium channels by micro-conotoxin KIIIA and saxitoxin or tetrodotoxin., Zhang MM., J Neurophysiol. July 1, 2010; 104 (1): 88-97.
	Fast and slow voltage sensor rearrangements during activation gating in Kv1.2 channels detected using tetramethylrhodamine fluorescence., Horne AJ., J Gen Physiol. July 1, 2010; 136 (1): 83-99.
	The N terminus of monoamine transporters is a lever required for the action of amphetamines., Sucic S., J Biol Chem. April 2, 2010; 285 (14): 10924-38.
	Conformational changes associated with proton-dependent gating of ASIC1a., Passero CJ., J Biol Chem. December 25, 2009; 284 (52): 36473-36481.
	An electrostatic interaction between TEA and an introduced pore aromatic drives spring-in-the-door inactivation in Shaker potassium channels., Ahern CA., J Gen Physiol. December 1, 2009; 134 (6): 461-9.
	The evolutionarily conserved residue A653 plays a key role in HERG channel closing., Stepanovic SZ., J Physiol. June 1, 2009; 587 (Pt 11): 2555-66.
	The analysis of desensitizing CNGA1 channels reveals molecular interactions essential for normal gating., Mazzolini M., J Gen Physiol. April 1, 2009; 133 (4): 375-86.
	Four Ca2+ ions activate TRPM2 channels by binding in deep crevices near the pore but intracellularly of the gate., Csanády L., J Gen Physiol. February 1, 2009; 133 (2): 189-203.
	K+ binding in the G-loop and water cavity facilitates Ba2+ movement in the Kir2.1 channel., Chang HK., Biochim Biophys Acta. February 1, 2009; 1788 (2): 500-6.
	The ion pathway through the opened Na(+),K(+)-ATPase pump., Takeuchi A., Nature. November 20, 2008; 456 (7220): 413-6.
	Differential effects of linear and cyclic polyamines on NMDA receptor activities., Masuko T., Neurochem Int. July 1, 2008; 53 (1-2): 38-44.
	Is TEA an inhibitor for human Aquaporin-1?, Müller EM., Pflugers Arch. July 1, 2008; 456 (4): 663-9.
	Probing the binding sites and mechanisms of action of two human ether-a-go-go-related gene channel activators, 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643) and 2-[2-(3,4-dichloro-phenyl)-2,3-dihydro-1H-isoindol-5-ylamino]-nicotinic acid (PD307243)., Xu X., Mol Pharmacol. June 1, 2008; 73 (6): 1709-21.
	Molecular determinants of the anticonvulsant felbamate binding site in the N-methyl-D-aspartate receptor., Chang HR., J Med Chem. March 27, 2008; 51 (6): 1534-45.
	Mutations at arginine 352 alter the pore architecture of CFTR., Cui G., J Membr Biol. March 1, 2008; 222 (2): 91-106.
	Intrinsic electrostatic potential in the BK channel pore: role in determining single channel conductance and block., Carvacho I., J Gen Physiol. February 1, 2008; 131 (2): 147-61.
	Speeding the recovery from ultraslow inactivation of voltage-gated Na+ channels by metal ion binding to the selectivity filter: a foot-on-the-door?, Szendroedi J., Biophys J. December 15, 2007; 93 (12): 4209-24.
	Cleft-type cyclophanes confer neuroprotection against excitatory neurotoxicity in vitro and in vivo through inhibition of NMDA receptors., Masuko T., Neuropharmacology. September 1, 2007; 53 (4): 515-23.
	Voltage-independent sodium-binding events reported by the 4B-4C loop in the human glutamate transporter excitatory amino acid transporter 3., Koch HP., J Biol Chem. August 24, 2007; 282 (34): 24547-53.
	Chromanol 293B binding in KCNQ1 (Kv7.1) channels involves electrostatic interactions with a potassium ion in the selectivity filter., Lerche C., Mol Pharmacol. June 1, 2007; 71 (6): 1503-11.
	Probing the outer mouth structure of the HERG channel with peptide toxin footprinting and molecular modeling., Tseng GN., Biophys J. May 15, 2007; 92 (10): 3524-40.
	Structural determinants of the closed KCa3.1 channel pore in relation to channel gating: results from a substituted cysteine accessibility analysis., Klein H., J Gen Physiol. April 1, 2007; 129 (4): 299-315.
	A cation-pi interaction discriminates among sodium channels that are either sensitive or resistant to tetrodotoxin block., Santarelli VP., J Biol Chem. March 16, 2007; 282 (11): 8044-51.
	Cyclophane and acyclic cyclophane: novel channel blockers of N-methyl-D-aspartate receptor., Masuko T., Neurochem Int. January 1, 2007; 50 (2): 443-9.
	A highly conserved hydrophobic motif in the exofacial vestibule of fructose transporting SLC2A proteins acts as a critical determinant of their substrate selectivity., Manolescu AR., Mol Membr Biol. January 1, 2007; 24 (5-6): 455-63.
	Docking of mu-conotoxin GIIIA in the sodium channel outer vestibule., Choudhary G., Channels (Austin). January 1, 2007; 1 (5): 344-52.
	NR3A modulates the outer vestibule of the "NMDA" receptor channel., Wada A., J Neurosci. December 20, 2006; 26 (51): 13156-66.
	A conserved ring of charge in mammalian Na+ channels: a molecular regulator of the outer pore conformation during slow inactivation., Xiong W., J Physiol. November 1, 2006; 576 (Pt 3): 739-54.
	Ion permeation through the Na+,K+-ATPase., Reyes N., Nature. September 28, 2006; 443 (7110): 470-4.

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