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Mutational analysis to explore long-range allosteric couplings involved in a pentameric channel receptor pre-activation and activation. , Lefebvre SN., Elife. September 30, 2021; 10
Translocation of TMEM175 Lysosomal Potassium Channel to the Plasma Membrane by Dynasore Compounds. , Pergel E., Int J Mol Sci. September 29, 2021; 22 (19):
Ttc30a affects tubulin modifications in a model for ciliary chondrodysplasia with polycystic kidney disease. , Getwan M ., Proc Natl Acad Sci U S A. September 28, 2021; 118 (39):
Cell-cell contact landscapes in Xenopus gastrula tissues. , Barua D., Proc Natl Acad Sci U S A. September 28, 2021; 118 (39):
SUMOylation Potentiates ZIC Protein Activity to Influence Murine Neural Crest Cell Specification. , Bellchambers HM., Int J Mol Sci. September 28, 2021; 22 (19):
Polo-like kinase 1 (Plk1) regulates DNA replication origin firing and interacts with Rif1 in Xenopus. , Ciardo D., Nucleic Acids Res. September 27, 2021; 49 (17): 9851-9869.
Dynorphin Neuropeptides Decrease Apparent Proton Affinity of ASIC1a by Occluding the Acidic Pocket. , Leisle L., J Med Chem. September 23, 2021; 64 (18): 13299-13311.
Bicc1 and Dicer regulate left- right patterning through post-transcriptional control of the Nodal inhibitor Dand5. , Maerker M., Nat Commun. September 16, 2021; 12 (1): 5482.
Physical basis for distinct basal and mechanically gated activity of the human K+ channel TRAAK. , Rietmeijer RA., Neuron. September 15, 2021; 109 (18): 2902-2913.e4.
Tril dampens Nodal signaling through Pellino2- and Traf6-mediated activation of Nedd4l. , Kim HS ., Proc Natl Acad Sci U S A. September 7, 2021; 118 (36):
Foxm1 regulates neural progenitor fate during spinal cord regeneration. , Pelzer D., EMBO Rep. September 6, 2021; 22 (9): e50932.
Characterization of a Compound Heterozygous SLC2A9 Mutation That Causes Hypouricemia. , Yoon J., Biomedicines. September 6, 2021; 9 (9):
Protein phosphatase 2A holoenzymes regulate leucine-rich repeat kinase 2 phosphorylation and accumulation. , Drouyer M., Neurobiol Dis. September 1, 2021; 157 105426.
Sobp modulates the transcriptional activation of Six1 target genes and is required during craniofacial development. , Tavares ALP., Development. September 1, 2021; 148 (17):
A systemic cell cycle block impacts stage-specific histone modification profiles during Xenopus embryogenesis. , Pokrovsky D., PLoS Biol. September 1, 2021; 19 (9): e3001377.
Single-minded 2 is required for left- right asymmetric stomach morphogenesis. , Wyatt BH., Development. September 1, 2021; 148 (17):
Ptk7 Is Dynamically Localized at Neural Crest Cell-Cell Contact Sites and Functions in Contact Inhibition of Locomotion. , Grund A., Int J Mol Sci. August 28, 2021; 22 (17):
The dual-specificity protein kinase Clk3 is essential for Xenopus neural development. , Virgirinia RP., Biochem Biophys Res Commun. August 27, 2021; 567 99-105.
The Cytoskeleton and Its Roles in Self-Organization Phenomena: Insights from Xenopus Egg Extracts. , Geisterfer ZM., Cells. August 26, 2021; 10 (9):
Auto-inhibitory intramolecular S5/S6 interaction in the TRPV6 channel regulates breast cancer cell migration and invasion. , Cai R., Commun Biol. August 19, 2021; 4 (1): 990.
Linker histone H1.8 inhibits chromatin binding of condensins and DNA topoisomerase II to tune chromosome length and individualization. , Choppakatla P., Elife. August 18, 2021; 10
Cation leak underlies neuronal excitability in an HCN1 developmental and epileptic encephalopathy. , Bleakley LE., Brain. August 17, 2021; 144 (7): 2060-2073.
Functional cross-talk between phosphorylation and disease-causing mutations in the cardiac sodium channel Nav1.5. , Galleano I., Proc Natl Acad Sci U S A. August 17, 2021; 118 (33):
A polycystin-2 protein with modified channel properties leads to an increased diameter of renal tubules and to renal cysts. , Grosch M., J Cell Sci. August 15, 2021; 134 (16):
The Transcription Factor NF-κB in Stem Cells and Development. , Kaltschmidt C., Cells. August 10, 2021; 10 (8):
Generation of anisotropic strain dysregulates wild-type cell division at the interface between host and oncogenic tissue. , Moruzzi M., Curr Biol. August 9, 2021; 31 (15): 3409-3418.e6.
TGF-β1 signaling is essential for tissue regeneration in the Xenopus tadpole tail. , Nakamura M., Biochem Biophys Res Commun. August 6, 2021; 565 91-96.
GluN2A and GluN2B NMDA receptors use distinct allosteric routes. , Tian M., Nat Commun. August 5, 2021; 12 (1): 4709.
Haploinsufficiency of SF3B2 causes craniofacial microsomia. , Timberlake AT., Nat Commun. August 3, 2021; 12 (1): 4680.
Retinol binding protein 1 affects Xenopus anterior neural development via all-trans retinoic acid signaling. , Flach H., Dev Dyn. August 1, 2021; 250 (8): 1096-1112.
Evaluating the Arrhenius equation for developmental processes. , Crapse J., Mol Syst Biol. August 1, 2021; 17 (8): e9895.
Conserved role of the urotensin II receptor 4 signalling pathway to control body straightness in a tetrapod. , Alejevski F., Open Biol. August 1, 2021; 11 (8): 210065.
Cross-talk-dependent cortical patterning of Rho GTPases during cell repair. , Moe A., Mol Biol Cell. August 1, 2021; 32 (16): 1417-1432.
ZC3HC1 Is a Novel Inherent Component of the Nuclear Basket, Resident in a State of Reciprocal Dependence with TPR. , Gunkel P., Cells. July 30, 2021; 10 (8):
Role of matrix metalloproteinase-9 in neurodevelopmental deficits and experience-dependent plasticity in Xenopus laevis. , Gore SV., Elife. July 20, 2021; 10
Rab7 is required for mesoderm patterning and gastrulation in Xenopus. , Kreis J., Biol Open. July 15, 2021; 10 (7):
Temporal transcriptomic profiling reveals dynamic changes in gene expression of Xenopus animal cap upon activin treatment. , Satou-Kobayashi Y., Sci Rep. July 15, 2021; 11 (1): 14537.
The dorsal blastopore lip is a source of signals inducing planar cell polarity in the Xenopus neural plate. , Mancini P ., Biol Open. July 15, 2021; 10 (7):
Twinfilin1 controls lamellipodial protrusive activity and actin turnover during vertebrate gastrulation. , Devitt CC., J Cell Sci. July 15, 2021; 134 (14):
Resolving different presynaptic activity patterns within single olfactory glomeruli of Xenopus laevis larvae. , Topci R., Sci Rep. July 9, 2021; 11 (1): 14258.
Crosstalk between repair pathways elicits double-strand breaks in alkylated DNA and implications for the action of temozolomide. , Fuchs RP., Elife. July 8, 2021; 10
The Wnt/PCP formin Daam1 drives cell-cell adhesion during nephron development. , Krneta-Stankic V., Cell Rep. July 6, 2021; 36 (1): 109340.
Identification of a gustatory receptor tuned to sinigrin in the cabbage butterfly Pieris rapae. , Yang J ., PLoS Genet. July 6, 2021; 17 (7): e1009527.
Axon terminals control endolysosome diffusion to support synaptic remodelling. , Terni B., Life Sci Alliance. July 5, 2021; 4 (8):
The molecular basis of coupling between poly(A)- tail length and translational efficiency. , Xiang K., Elife. July 2, 2021; 10
Two de novo GluN2B mutations affect multiple NMDAR-functions and instigate severe pediatric encephalopathy. , Kellner S., Elife. July 2, 2021; 10
DLG5 variants are associated with multiple congenital anomalies including ciliopathy phenotypes. , Marquez J ., J Med Genet. July 1, 2021; 58 (7): 453-464.
Tau, XMAP215/Msps and Eb1 co-operate interdependently to regulate microtubule polymerisation and bundle formation in axons. , Hahn I., PLoS Genet. July 1, 2021; 17 (7): e1009647.
Structural insight into BRCA1- BARD1 complex recruitment to damaged chromatin. , Dai L., Mol Cell. July 1, 2021; 81 (13): 2765-2777.e6.
Mutations in SIX1 Associated with Branchio-oto-Renal Syndrome (BOR) Differentially Affect Otic Expression of Putative Target Genes. , Mehdizadeh T., J Dev Biol. June 30, 2021; 9 (3):