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Molecular site of action of the antiarrhythmic drug propafenone at the voltage-operated potassium channel Kv2.1. , Madeja M., Mol Pharmacol. March 1, 2003; 63 (3): 547-56.
BeKm-1 is a HERG-specific toxin that shares the structure with ChTx but the mechanism of action with ErgTx1. , Zhang M., Biophys J. May 1, 2003; 84 (5): 3022-36.
Local anesthetic block of Kv channels: role of the S6 helix and the S5-S6 linker for bupivacaine action. , Nilsson J., Mol Pharmacol. June 1, 2003; 63 (6): 1417-29.
Three-dimensional morphology of inner ear development in Xenopus laevis. , Bever MM., Dev Dyn. July 1, 2003; 227 (3): 422-30.
A ring of eight conserved negatively charged amino acids doubles the conductance of BK channels and prevents inward rectification. , Brelidze TI., Proc Natl Acad Sci U S A. July 22, 2003; 100 (15): 9017-22.
External TEA block of shaker K+ channels is coupled to the movement of K+ ions within the selectivity filter. , Thompson J ., J Gen Physiol. August 1, 2003; 122 (2): 239-46.
Beta1 subunits facilitate gating of BK channels by acting through the Ca2+, but not the Mg2+, activating mechanisms. , Qian X., Proc Natl Acad Sci U S A. August 19, 2003; 100 (17): 10061-6.
Agonist-induced conformational changes in the extracellular domain of alpha 7 nicotinic acetylcholine receptors. , Lyford LK., Mol Pharmacol. September 1, 2003; 64 (3): 650-8.
Gating competence of constitutively open CLC-0 mutants revealed by the interaction with a small organic Inhibitor. , Traverso S., J Gen Physiol. September 1, 2003; 122 (3): 295-306.
Molecular basis of calcium regulation in connexin-32 hemichannels. , Gómez-Hernández JM., Proc Natl Acad Sci U S A. December 23, 2003; 100 (26): 16030-5.
Outer pore topology of the ECaC- TRPV5 channel by cysteine scan mutagenesis. , Dodier Y., J Biol Chem. February 20, 2004; 279 (8): 6853-62.
Protons block BK channels by competitive inhibition with K+ and contribute to the limits of unitary currents at high voltages. , Brelidze TI., J Gen Physiol. March 1, 2004; 123 (3): 305-19.
Cloning and expression of a small-conductance Ca(2+)-activated K+ channel from the mouse cochlea: coexpression with alpha9/alpha10 acetylcholine receptors. , Nie L., J Neurophysiol. April 1, 2004; 91 (4): 1536-44.
Molecular basis of pH and Ca2+ regulation of aquaporin water permeability. , Németh-Cahalan KL., J Gen Physiol. May 1, 2004; 123 (5): 573-80.
Anthraquinone polyamines: novel channel blockers to study N-methyl-D-aspartate receptors. , Kashiwagi K ., J Pharmacol Exp Ther. June 1, 2004; 309 (3): 884-93.
Regulation of K+ flow by a ring of negative charges in the outer pore of BKCa channels. Part I: Aspartate 292 modulates K+ conduction by external surface charge effect. , Haug T., J Gen Physiol. August 1, 2004; 124 (2): 173-84.
The role of Pax2 in mouse inner ear development. , Burton Q., Dev Biol. August 1, 2004; 272 (1): 161-75.
Lidocaine: a foot in the door of the inner vestibule prevents ultra-slow inactivation of a voltage-gated sodium channel. , Sandtner W., Mol Pharmacol. September 1, 2004; 66 (3): 648-57.
Three mechanisms underlie KCNQ2/3 heteromeric potassium M-channel potentiation. , Etxeberria A., J Neurosci. October 13, 2004; 24 (41): 9146-52.
Molecular basis of inward rectification: polyamine interaction sites located by combined channel and ligand mutagenesis. , Kurata HT., J Gen Physiol. November 1, 2004; 124 (5): 541-54.
Inhibition of CFTR channels by a peptide toxin of scorpion venom. , Fuller MD., Am J Physiol Cell Physiol. November 1, 2004; 287 (5): C1328-41.
State-dependent changes in the electrostatic potential in the pore of a GluR channel. , Sobolevsky AI., Biophys J. January 1, 2005; 88 (1): 235-42.
A ring of negative charges in the intracellular vestibule of Kir2.1 channel modulates K+ permeation. , Chang HK., Biophys J. January 1, 2005; 88 (1): 243-54.
A multifunctional aromatic residue in the external pore vestibule of Na+ channels contributes to the local anesthetic receptor. , Tsang SY., Mol Pharmacol. February 1, 2005; 67 (2): 424-34.
Small-scale molecular motions accomplish glutamate uptake in human glutamate transporters. , Koch HP., J Neurosci. February 16, 2005; 25 (7): 1730-6.
Pharmacology of acetylcholine-mediated cell signaling in the lateral line organ following efferent stimulation. , Dawkins R., J Neurophysiol. May 1, 2005; 93 (5): 2541-51.
Cysteine accessibility in ClC-0 supports conservation of the ClC intracellular vestibule. , Engh AM., J Gen Physiol. June 1, 2005; 125 (6): 601-17.
Probing the geometry of the inner vestibule of BK channels with sugars. , Brelidze TI., J Gen Physiol. August 1, 2005; 126 (2): 105-21.
Slow inactivation in voltage gated potassium channels is insensitive to the binding of pore occluding peptide toxins. , Oliva C., Biophys J. August 1, 2005; 89 (2): 1009-19.
A novel alpha-conotoxin, PeIA, cloned from Conus pergrandis, discriminates between rat alpha9alpha10 and alpha7 nicotinic cholinergic receptors. , McIntosh JM., J Biol Chem. August 26, 2005; 280 (34): 30107-12.
Pharmacological implications of two distinct mechanisms of interaction of memantine with N-methyl-D-aspartate-gated channels. , Chen HS ., J Pharmacol Exp Ther. September 1, 2005; 314 (3): 961-71.
Expression and functional phenotype of mouse ERG K+ channels in the inner ear: potential role in K+ regulation in the inner ear. , Nie L., J Neurosci. September 21, 2005; 25 (38): 8671-9.
EYA1 expression in the developing inner ear. , Bane BC., Ann Otol Rhinol Laryngol. November 1, 2005; 114 (11): 853-8.
Inner ear formation during the early larval development of Xenopus laevis. , Quick QA ., Dev Dyn. November 1, 2005; 234 (3): 791-801.
Stoichiometry of the alpha9alpha10 nicotinic cholinergic receptor. , Plazas PV., J Neurosci. November 23, 2005; 25 (47): 10905-12.
An inhibitor of TRPV1 channels isolated from funnel Web spider venom. , Kitaguchi T., Biochemistry. November 29, 2005; 44 (47): 15544-9.
Electrostatics in the cytoplasmic pore produce intrinsic inward rectification in kir2.1 channels. , Yeh SH., J Gen Physiol. December 1, 2005; 126 (6): 551-62.
Identification of a hydrophobic residue as a key determinant of fructose transport by the facilitative hexose transporter SLC2A7 ( GLUT7). , Manolescu A., J Biol Chem. December 30, 2005; 280 (52): 42978-83.
Pharmacology and surface electrostatics of the K channel outer pore vestibule. , Quinn CC., J Membr Biol. January 1, 2006; 212 (1): 51-60.
Alpha-RgIA: a novel conotoxin that specifically and potently blocks the alpha9alpha10 nAChR. , Ellison M., Biochemistry. February 7, 2006; 45 (5): 1511-7.
Allosteric effects of external K+ ions mediated by the aspartate of the GYGD signature sequence in the Kv2.1 K+ channel. , Chapman ML., Pflugers Arch. March 1, 2006; 451 (6): 776-92.
Loss of function mutations of the GJB2 gene detected in patients with DFNB1-associated hearing impairment. , Palmada M ., Neurobiol Dis. April 1, 2006; 22 (1): 112-8.
Access of quaternary ammonium blockers to the internal pore of cyclic nucleotide-gated channels: implications for the location of the gate. , Contreras JE., J Gen Physiol. May 1, 2006; 127 (5): 481-94.
Dishevelled genes mediate a conserved mammalian PCP pathway to regulate convergent extension during neurulation. , Wang J ., Development. May 1, 2006; 133 (9): 1767-78.
Ring of negative charge in BK channels facilitates block by intracellular Mg2+ and polyamines through electrostatics. , Zhang Y ., J Gen Physiol. August 1, 2006; 128 (2): 185-202.
Ouabain affinity determining residues lie close to the Na/K pump ion pathway. , Artigas P., Proc Natl Acad Sci U S A. August 15, 2006; 103 (33): 12613-8.
Ion permeation through the Na+,K+-ATPase. , Reyes N., Nature. September 28, 2006; 443 (7110): 470-4.
Mutations of connexin 26 at position 75 and dominant deafness: essential role of arginine for the generation of functional gap-junctional channels. , Deng Y., Hear Res. October 1, 2006; 220 (1-2): 87-94.
A conserved ring of charge in mammalian Na+ channels: a molecular regulator of the outer pore conformation during slow inactivation. , Xiong W., J Physiol. November 1, 2006; 576 (Pt 3): 739-54.
NR3A modulates the outer vestibule of the "NMDA" receptor channel. , Wada A., J Neurosci. December 20, 2006; 26 (51): 13156-66.