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Summary Anatomy Item Literature (2463) Expression Attributions Wiki
XB-ANAT-63

Papers associated with heart (and pitx2)

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A homozygous human WNT11 variant is associated with laterality, heart and renal defects., Berns H., Dis Model Mech. April 9, 2025;   


CIROZ is dispensable in ancestral vertebrates but essential for left-right patterning in humans., Szenker-Ravi E., Am J Hum Genet. January 6, 2025; 112 (2): 353-373.


The Heterotaxy Gene CCDC11 Is Important for Cytokinesis via RhoA Regulation., Kulkarni SS., Cytoskeleton (Hoboken). October 31, 2024;   


CC2D1A causes ciliopathy, intellectual disability, heterotaxy, renal dysplasia, and abnormal CSF flow., Kim AH., Life Sci Alliance. October 21, 2024; 7 (10):   


R-Spondin 2 governs Xenopus left-right body axis formation by establishing an FGF signaling gradient., Lee H., Nat Commun. February 2, 2024; 15 (1): 1003.   


CFAP45, a heterotaxy and congenital heart disease gene, affects cilia stability., Deniz E., Dev Biol. July 1, 2023; 499 75-88.   


Pleiotropic role of TRAF7 in skull-base meningiomas and congenital heart disease., Mishra-Gorur K., Proc Natl Acad Sci U S A. April 18, 2023; 120 (16): e2214997120.   


Mink1 regulates spemann organizer cell fate in the xenopus gastrula via Hmga2., Colleluori V., Dev Biol. March 1, 2023; 495 42-53.   


Membrane potential drives the exit from pluripotency and cell fate commitment via calcium and mTOR., Sempou E., Nat Commun. November 5, 2022; 13 (1): 6681.   


Maternal Wnt11b regulates cortical rotation during Xenopus axis formation: analysis of maternal-effect wnt11b mutants., Houston DW., Development. September 1, 2022; 149 (17):   


GJA1 depletion causes ciliary defects by affecting Rab11 trafficking to the ciliary base., Jang DG., Elife. August 25, 2022; 11   


Normal Table of Xenopus development: a new graphical resource., Zahn N., Development. July 15, 2022; 149 (14):   


HMCES modulates the transcriptional regulation of nodal/activin and BMP signaling in mESCs., Liang T., Cell Rep. July 12, 2022; 40 (2): 111038.   


Abnormal left-right organizer and laterality defects in Xenopus embryos after formin inhibitor SMIFH2 treatment., Petri N., PLoS One. January 1, 2022; 17 (11): e0275164.   


Altering metabolite distribution at Xenopus cleavage stages affects left-right gene expression asymmetries., Onjiko RM., Genesis. June 1, 2021; 59 (5-6): e23418.   


RNA demethylation by FTO stabilizes the FOXJ1 mRNA for proper motile ciliogenesis., Kim H., Dev Cell. April 19, 2021; 56 (8): 1118-1130.e6.   


Nucleoporin NUP205 plays a critical role in cilia and congenital disease., Marquez J., Dev Biol. January 1, 2021; 469 46-53.   


Histone H2B monoubiquitination regulates heart development via epigenetic control of cilia motility., Robson A., Proc Natl Acad Sci U S A. July 9, 2019; 116 (28): 14049-14054.   


WDR5 regulates left-right patterning via chromatin-dependent and -independent functions., Kulkarni SS., Development. November 28, 2018; 145 (23):   


A Conserved Role of the Unconventional Myosin 1d in Laterality Determination., Tingler M., Curr Biol. March 5, 2018; 28 (5): 810-816.e3.   


RAPGEF5 Regulates Nuclear Translocation of β-Catenin., Griffin JN., Dev Cell. January 22, 2018; 44 (2): 248-260.e4.   


Candidate Heterotaxy Gene FGFR4 Is Essential for Patterning of the Left-Right Organizer in Xenopus., Sempou E., Front Physiol. January 1, 2018; 9 1705.   


Evolutionary Proteomics Uncovers Ancient Associations of Cilia with Signaling Pathways., Sigg MA., Dev Cell. December 18, 2017; 43 (6): 744-762.e11.   


HCN4 ion channel function is required for early events that regulate anatomical left-right patterning in a nodal and lefty asymmetric gene expression-independent manner., Pai VP., Biol Open. October 15, 2017; 6 (10): 1445-1457.   


Xenopus pitx3 target genes lhx1 and xnr5 are identified using a novel three-fluor flow cytometry-based analysis of promoter activation and repression., Hooker LN., Dev Dyn. September 1, 2017; 246 (9): 657-669.   


Id genes are essential for early heart formation., Cunningham TJ., Genes Dev. July 1, 2017; 31 (13): 1325-1338.   


Coordinating heart morphogenesis: A novel role for hyperpolarization-activated cyclic nucleotide-gated (HCN) channels during cardiogenesis in Xenopus laevis., Pitcairn E., Commun Integr Biol. May 10, 2017; 10 (3): e1309488.   


Leftward Flow Determines Laterality in Conjoined Twins., Tisler M., Curr Biol. February 20, 2017; 27 (4): 543-548.   


Congenital Heart Disease Genetics Uncovers Context-Dependent Organization and Function of Nucleoporins at Cilia., Del Viso F., Dev Cell. September 12, 2016; 38 (5): 478-92.   


Nodal signalling in Xenopus: the role of Xnr5 in left/right asymmetry and heart development., Tadjuidje E., Open Biol. August 1, 2016; 6 (8):   


Conserved roles for cytoskeletal components in determining laterality., McDowell GS., Integr Biol (Camb). March 14, 2016; 8 (3): 267-86.


Xenopus as a model organism for birth defects-Congenital heart disease and heterotaxy., Duncan AR., Semin Cell Dev Biol. March 1, 2016; 51 73-9.   


The NIMA-like kinase Nek2 is a key switch balancing cilia biogenesis and resorption in the development of left-right asymmetry., Endicott SJ., Development. December 1, 2015; 142 (23): 4068-79.   


The ribosome biogenesis factor Nol11 is required for optimal rDNA transcription and craniofacial development in Xenopus., Griffin JN., PLoS Genet. March 10, 2015; 11 (3): e1005018.   


Symmetry breakage in the frog Xenopus: role of Rab11 and the ventral-right blastomere., Tingler M., Genesis. June 1, 2014; 52 (6): 588-99.   


The evolution and conservation of left-right patterning mechanisms., Blum M., Development. April 1, 2014; 141 (8): 1603-13.   


Left-right asymmetry: lessons from Cancún., Burdine RD., Development. November 1, 2013; 140 (22): 4465-70.   


It's never too early to get it Right: A conserved role for the cytoskeleton in left-right asymmetry., Vandenberg LN., Commun Integr Biol. November 1, 2013; 6 (6): e27155.   


Xenopus laevis nucleotide binding protein 1 (xNubp1) is important for convergent extension movements and controls ciliogenesis via regulation of the actin cytoskeleton., Ioannou A., Dev Biol. August 15, 2013; 380 (2): 243-58.   


Serotonin has early, cilia-independent roles in Xenopus left-right patterning., Vandenberg LN., Dis Model Mech. January 1, 2013; 6 (1): 261-8.   


ATP4a is required for Wnt-dependent Foxj1 expression and leftward flow in Xenopus left-right development., Walentek P., Cell Rep. May 31, 2012; 1 (5): 516-27.   


Connexin26-mediated transfer of laterality cues in Xenopus., Beyer T., Biol Open. May 15, 2012; 1 (5): 473-81.   


Myogenic waves and myogenic programs during Xenopus embryonic myogenesis., Della Gaspera B., Dev Dyn. May 1, 2012; 241 (5): 995-1007.   


An essential and highly conserved role for Zic3 in left-right patterning, gastrulation and convergent extension morphogenesis., Cast AE., Dev Biol. April 1, 2012; 364 (1): 22-31.   


Linking early determinants and cilia-driven leftward flow in left-right axis specification of Xenopus laevis: a theoretical approach., Schweickert A., Differentiation. February 1, 2012; 83 (2): S67-77.   


Neurally Derived Tissues in Xenopus laevis Embryos Exhibit a Consistent Bioelectrical Left-Right Asymmetry., Pai VP., Stem Cells Int. January 1, 2012; 2012 353491.   


IP3 signaling is required for cilia formation and left-right body axis determination in Xenopus embryos., Hatayama M., Biochem Biophys Res Commun. July 8, 2011; 410 (3): 520-4.   


Rare copy number variations in congenital heart disease patients identify unique genes in left-right patterning., Fakhro KA., Proc Natl Acad Sci U S A. February 15, 2011; 108 (7): 2915-20.   


BCL6 canalizes Notch-dependent transcription, excluding Mastermind-like1 from selected target genes during left-right patterning., Sakano D., Dev Cell. March 16, 2010; 18 (3): 450-62.   


Retinoic acid regulates anterior-posterior patterning within the lateral plate mesoderm of Xenopus., Deimling SJ., Mech Dev. October 1, 2009; 126 (10): 913-23.   

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