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Extracellular cysteine disulfide bond break at Cys122 disrupts PIP 2 -dependent Kir2.1 channel function and leads to arrhythmias in Andersen-Tawil Syndrome. , Cruz FM., bioRxiv. June 8, 2023;
Class III antiarrhythmic drug dronedarone inhibits cardiac inwardly rectifying Kir2.1 channels through binding at residue E224. , Xynogalos P., Naunyn Schmiedebergs Arch Pharmacol. December 1, 2014; 387 (12): 1153-61.
Up-regulation of Kir2.1 ( KCNJ2) by the serum & glucocorticoid inducible SGK3. , Munoz C., Cell Physiol Biochem. January 1, 2014; 33 (2): 491-500.
Inhibition of Kir2.1 ( KCNJ2) by the AMP-activated protein kinase. , Alesutan I., Biochem Biophys Res Commun. May 20, 2011; 408 (4): 505-10.
Kir2.x inward rectifier potassium channels are differentially regulated by adrenergic alpha1A receptors. , Zitron E., J Mol Cell Cardiol. January 1, 2008; 44 (1): 84-94.
Activation of inwardly rectifying Kir2.x potassium channels by beta 3-adrenoceptors is mediated via different signaling pathways with a predominant role of PKC for Kir2.1 and of PKA for Kir2.2. , Scherer D., Naunyn Schmiedebergs Arch Pharmacol. July 1, 2007; 375 (5): 311-22.
Unitary conductance variation in Kir2.1 and in cardiac inward rectifier potassium channels. , Picones A., Biophys J. October 1, 2001; 81 (4): 2035-49.
The role of Kir2.1 in the genesis of native cardiac inward-rectifier K+ currents during pre- and postnatal development. , Nakamura TY., Ann N Y Acad Sci. April 30, 1999; 868 434-7.
Suppression of Kir2.3 activity by protein kinase C phosphorylation of the channel protein at threonine 53. , Zhu G., J Biol Chem. April 23, 1999; 274 (17): 11643-6.