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R-Spondin 2 governs Xenopus left- right body axis formation by establishing an FGF signaling gradient. , Lee H , Lee H ., Nat Commun. February 2, 2024; 15 (1): 1003.
Uncoupling the BMP receptor antagonist function from the WNT agonist function of R-spondin 2 using the inhibitory peptide dendrimer RWd. , Lee H , Lee H ., J Biol Chem. February 1, 2022; 298 (2): 101586.
Rspo2 inhibits TCF3 phosphorylation to antagonize Wnt signaling during vertebrate anteroposterior axis specification. , Reis AH., Sci Rep. June 28, 2021; 11 (1): 13433.
Secreted inhibitors drive the loss of regeneration competence in Xenopus limbs. , Aztekin C ., Development. June 1, 2021; 148 (11):
R-spondins are BMP receptor antagonists in Xenopus early embryonic development. , Lee H , Lee H ., Nat Commun. November 4, 2020; 11 (1): 5570.
ΔN- Tp63 Mediates Wnt/ β-Catenin-Induced Inhibition of Differentiation in Basal Stem Cells of Mucociliary Epithelia. , Haas M., Cell Rep. September 24, 2019; 28 (13): 3338-3352.e6.
Evolutionarily conserved Tbx5-Wnt2/2b pathway orchestrates cardiopulmonary development. , Steimle JD., Proc Natl Acad Sci U S A. November 6, 2018; 115 (45): E10615-E10624.
The Wnt signaling regulator R-spondin 3 promotes angioblast and vascular development. , Kazanskaya O., Development. November 1, 2008; 135 (22): 3655-64.
R-Spondin2 is a secreted activator of Wnt/beta-catenin signaling and is required for Xenopus myogenesis. , Kazanskaya O., Dev Cell. October 1, 2004; 7 (4): 525-34.