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Summary Anatomy Item Literature (4908) Expression Attributions Wiki
XB-ANAT-3713

Papers associated with left (and kcnq1)

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Distinctive mechanisms of epilepsy-causing mutants discovered by measuring S4 movement in KCNQ2 channels., Edmond MA., Elife. June 1, 2022; 11   


Pharmacological rescue of specific long QT variants of KCNQ1/KCNE1 channels., Zou X., Front Physiol. January 1, 2022; 13 902224.   


Compound Heterozygous KCNQ1 Mutations Causing Recessive Romano-Ward Syndrome: Functional Characterization by Mutant Co-expression., González-Garrido A., Front Cardiovasc Med. February 22, 2021; 8 625449.


In vitro and in vivo characterization of Lu AA41178: A novel, brain penetrant, pan-selective Kv7 potassium channel opener with efficacy in preclinical models of epileptic seizures and psychiatric disorders., Grupe M., Eur J Pharmacol. November 15, 2020; 887 173440.


Structure and physiological function of the human KCNQ1 channel voltage sensor intermediate state., Taylor KC., Elife. February 25, 2020; 9   


Deconstruction of an African folk medicine uncovers a novel molecular strategy for therapeutic potassium channel activation., De Silva AM., Sci Adv. November 14, 2018; 4 (11): eaav0824.   


Ancient and modern anticonvulsants act synergistically in a KCNQ potassium channel binding pocket., Manville RW., Nat Commun. September 21, 2018; 9 (1): 3845.   


Direct neurotransmitter activation of voltage-gated potassium channels., Manville RW., Nat Commun. May 10, 2018; 9 (1): 1847.   


Inactivation of KCNQ1 potassium channels reveals dynamic coupling between voltage sensing and pore opening., Hou P., Nat Commun. November 23, 2017; 8 (1): 1730.   


Bioelectric signalling via potassium channels: a mechanism for craniofacial dysmorphogenesis in KCNJ2-associated Andersen-Tawil Syndrome., Adams DS., J Physiol. June 15, 2016; 594 (12): 3245-70.   


High incidence of functional ion-channel abnormalities in a consecutive Long QT cohort with novel missense genetic variants of unknown significance., Steffensen AB., Sci Rep. January 12, 2015; 5 10009.   


Semicircular canal morphogenesis in the zebrafish inner ear requires the function of gpr126 (lauscher), an adhesion class G protein-coupled receptor gene., Geng FS., Development. November 1, 2013; 140 (21): 4362-74.   


Rab GTPases are required for early orientation of the left-right axis in Xenopus., Vandenberg LN., Mech Dev. January 1, 2013; 130 (4-5): 254-71.   


Impaired ion channel function related to a common KCNQ1 mutation - implications for risk stratification in long QT syndrome 1., Aidery P., Gene. December 10, 2012; 511 (1): 26-33.   


KCNQ1 subdomains involved in KCNE modulation revealed by an invertebrate KCNQ1 orthologue., Nakajo K., J Gen Physiol. November 1, 2011; 138 (5): 521-35.   


State-dependent electrostatic interactions of S4 arginines with E1 in S2 during Kv7.1 activation., Wu D., J Gen Physiol. June 1, 2010; 135 (6): 595-606.   


Selective interaction of syntaxin 1A with KCNQ2: possible implications for specific modulation of presynaptic activity., Regev N., PLoS One. August 13, 2009; 4 (8): e6586.   


Discovery of a novel activator of KCNQ1-KCNE1 K channel complexes., Mruk K., PLoS One. January 1, 2009; 4 (1): e4236.   


Modulation of potassium channel function confers a hyperproliferative invasive phenotype on embryonic stem cells., Morokuma J., Proc Natl Acad Sci U S A. October 28, 2008; 105 (43): 16608-13.   


KCNQ1 and KCNE1 in the IKs channel complex make state-dependent contacts in their extracellular domains., Xu X., J Gen Physiol. June 1, 2008; 131 (6): 589-603.   


S1 constrains S4 in the voltage sensor domain of Kv7.1 K+ channels., Haitin Y., PLoS One. April 9, 2008; 3 (4): e1935.   


KCNE peptides differently affect voltage sensor equilibrium and equilibration rates in KCNQ1 K+ channels., Rocheleau JM., J Gen Physiol. January 1, 2008; 131 (1): 59-68.   


KCNQ1 and KCNE1 K+ channel components are involved in early left-right patterning in Xenopus laevis embryos., Morokuma J., Cell Physiol Biochem. January 1, 2008; 21 (5-6): 357-72.


KCNE1 and KCNE3 stabilize and/or slow voltage sensing S4 segment of KCNQ1 channel., Nakajo K., J Gen Physiol. September 1, 2007; 130 (3): 269-81.   


The role of S4 charges in voltage-dependent and voltage-independent KCNQ1 potassium channel complexes., Panaghie G., J Gen Physiol. February 1, 2007; 129 (2): 121-33.   


Secondary structure of a KCNE cytoplasmic domain., Rocheleau JM., J Gen Physiol. December 1, 2006; 128 (6): 721-9.   


KCNE3 truncation mutants reveal a bipartite modulation of KCNQ1 K+ channels., Gage SD., J Gen Physiol. December 1, 2004; 124 (6): 759-71.   


External barium affects the gating of KCNQ1 potassium channels and produces a pore block via two discrete sites., Gibor G., J Gen Physiol. July 1, 2004; 124 (1): 83-102.   

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