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Advancements in the use of xenopus oocytes for modelling neurological disease for novel drug discovery. , O'Connor EC., Expert Opin Drug Discov. February 1, 2024; 19 (2): 173-187.
Cation leak underlies neuronal excitability in an HCN1 developmental and epileptic encephalopathy. , Bleakley LE., Brain. August 17, 2021; 144 (7): 2060-2073.
External Cd2+ and protons activate the hyperpolarization-gated K+ channel KAT1 at the voltage sensor. , Zhou Y., J Gen Physiol. January 4, 2021; 153 (1):
Regulation of human cardiac potassium channels by full-length KCNE3 and KCNE4. , Abbott GW., Sci Rep. December 6, 2016; 6 38412.
An N-terminal deletion variant of HCN1 in the epileptic WAG/Rij strain modulates HCN current densities. , Wemhöner K., Front Mol Neurosci. November 3, 2015; 8 63.
Protein kinase C activation inhibits rat and human hyperpolarization activated cyclic nucleotide gated channel (HCN)1--mediated current in mammalian cells. , Reetz O., Cell Physiol Biochem. January 1, 2013; 31 (4-5): 532-41.
Asymmetric divergence in structure and function of HCN channel duplicates in Ciona intestinalis. , Jackson HA., PLoS One. January 1, 2012; 7 (11): e47590.
State-dependent accessibility of the P-S6 linker of pacemaker (HCN) channels supports a dynamic pore-to-gate coupling model. , Siu CW., J Membr Biol. July 1, 2009; 230 (1): 35-47.
Voltage sensor movement and cAMP binding allosterically regulate an inherently voltage-independent closed-open transition in HCN channels. , Chen S., J Gen Physiol. February 1, 2007; 129 (2): 175-88.
Hysteresis in the voltage dependence of HCN channels: conversion between two modes affects pacemaker properties. , Männikkö R., J Gen Physiol. March 1, 2005; 125 (3): 305-26.
Salt bridges and gating in the COOH-terminal region of HCN2 and CNGA1 channels. , Craven KB., J Gen Physiol. December 1, 2004; 124 (6): 663-77.
Changes in local S4 environment provide a voltage-sensing mechanism for mammalian hyperpolarization-activated HCN channels. , Bell DC., J Gen Physiol. January 1, 2004; 123 (1): 5-19.
Regulation of hyperpolarization-activated HCN channel gating and cAMP modulation due to interactions of COOH terminus and core transmembrane regions. , Wang J ., J Gen Physiol. September 1, 2001; 118 (3): 237-50.
Properties of hyperpolarization-activated pacemaker current defined by coassembly of HCN1 and HCN2 subunits and basal modulation by cyclic nucleotide. , Chen S., J Gen Physiol. May 1, 2001; 117 (5): 491-504.