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Summary Anatomy Item Literature (3729) Expression Attributions Wiki
XB-ANAT-99

Papers associated with cardiovascular system (and kcne1)

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Ancillary subunits and stimulation frequency determine the potency of chromanol 293B block of the KCNQ1 potassium channel., Bett GC., J Physiol. November 1, 2006; 576 (Pt 3): 755-67.


KCNE2 is colocalized with KCNQ1 and KCNE1 in cardiac myocytes and may function as a negative modulator of I(Ks) current amplitude in the heart., Wu DM., Heart Rhythm. December 1, 2006; 3 (12): 1469-80.


The role of S4 charges in voltage-dependent and voltage-independent KCNQ1 potassium channel complexes., Panaghie G., J Gen Physiol. February 1, 2007; 129 (2): 121-33.                      


Upregulation of KCNE1 induces QT interval prolongation in patients with chronic heart failure., Watanabe E., Circ J. April 1, 2007; 71 (4): 471-8.


A derivatized scorpion toxin reveals the functional output of heteromeric KCNQ1-KCNE K+ channel complexes., Morin TJ., ACS Chem Biol. July 20, 2007; 2 (7): 469-73.


KCNE1 and KCNE3 stabilize and/or slow voltage sensing S4 segment of KCNQ1 channel., Nakajo K., J Gen Physiol. September 1, 2007; 130 (3): 269-81.            


Serial perturbation of MinK in IKs implies an alpha-helical transmembrane span traversing the channel corpus., Chen H., Biophys J. October 1, 2007; 93 (7): 2332-40.


KCNQ1 mutation Q147R is associated with atrial fibrillation and prolonged QT interval., Lundby A., Heart Rhythm. December 1, 2007; 4 (12): 1532-41.


Counting membrane-embedded KCNE beta-subunits in functioning K+ channel complexes., Morin TJ., Proc Natl Acad Sci U S A. February 5, 2008; 105 (5): 1478-82.


KCNQ1 and KCNE1 in the IKs channel complex make state-dependent contacts in their extracellular domains., Xu X., J Gen Physiol. June 1, 2008; 131 (6): 589-603.                    


Mechanisms by which atrial fibrillation-associated mutations in the S1 domain of KCNQ1 slow deactivation of IKs channels., Restier L., J Physiol. September 1, 2008; 586 (17): 4179-91.


Modulation of potassium channel function confers a hyperproliferative invasive phenotype on embryonic stem cells., Morokuma J., Proc Natl Acad Sci U S A. October 28, 2008; 105 (43): 16608-13.                                  


Functional implications of KCNE subunit expression for the Kv7.5 (KCNQ5) channel., Roura-Ferrer M., Cell Physiol Biochem. January 1, 2009; 24 (5-6): 325-34.


PKC activation and PIP(2) depletion underlie biphasic regulation of IKs by Gq-coupled receptors., Matavel A., J Mol Cell Cardiol. May 1, 2009; 46 (5): 704-12.


Intracellular domains interactions and gated motions of I(KS) potassium channel subunits., Haitin Y., EMBO J. July 22, 2009; 28 (14): 1994-2005.


Stoichiometry of the KCNQ1 - KCNE1 ion channel complex., Nakajo K., Proc Natl Acad Sci U S A. November 2, 2010; 107 (44): 18862-7.


Transmembrane potential of GlyCl-expressing instructor cells induces a neoplastic-like conversion of melanocytes via a serotonergic pathway., Blackiston D., Dis Model Mech. January 1, 2011; 4 (1): 67-85.                


Inhibition of the heterotetrameric K+ channel KCNQ1/KCNE1 by the AMP-activated protein kinase., Alesutan I., Mol Membr Biol. February 1, 2011; 28 (2): 79-89.


KCNQ1 subdomains involved in KCNE modulation revealed by an invertebrate KCNQ1 orthologue., Nakajo K., J Gen Physiol. November 1, 2011; 138 (5): 521-35.                        


Reconstitution of KCNE1 into lipid bilayers: comparing the structural, dynamic, and activity differences in micelle and vesicle environments., Coey AT., Biochemistry. December 20, 2011; 50 (50): 10851-9.


Regulation of KCNQ1/KCNE1 by β-catenin., Wilmes J., Mol Membr Biol. January 1, 2012; 29 (3-4): 87-94.


Differential effects of ginsenoside metabolites on slowly activating delayed rectifier K(+) and KCNQ1 K(+) channel currents., Choi SH., J Ginseng Res. July 1, 2013; 37 (3): 324-31.          


Domain-domain interactions determine the gating, permeation, pharmacology, and subunit modulation of the IKs ion channel., Zaydman MA., Elife. March 12, 2014; 3 e03606.                        


Insulin suppresses IKs (KCNQ1/KCNE1) currents, which require β-subunit KCNE1., Wu M., Pflugers Arch. May 1, 2014; 466 (5): 937-46.


Functional assembly of Kv7.1/Kv7.5 channels with emerging properties on vascular muscle physiology., Oliveras A., Arterioscler Thromb Vasc Biol. July 1, 2014; 34 (7): 1522-30.


Polyunsaturated fatty acid analogs act antiarrhythmically on the cardiac IKs channel., Liin SI., Proc Natl Acad Sci U S A. May 5, 2015; 112 (18): 5714-9.          


The residue I257 at S4-S5 linker in KCNQ1 determines KCNQ1/KCNE1 channel sensitivity to 1-alkanols., Xie C., Acta Pharmacol Sin. January 1, 2016; 37 (1): 124-33.          


Molecular cloning and functional expression of the K + channel K V 7.1 and the regulatory subunit KCNE1 from equine myocardium., Pedersen PJ., Res Vet Sci. August 1, 2017; 113 79-86.


KCNE1 and KCNE3 modulate KCNQ1 channels by affecting different gating transitions., Barro-Soria R., Proc Natl Acad Sci U S A. August 29, 2017; 114 (35): E7367-E7376.


Probing the Dynamics and Structural Topology of the Reconstituted Human KCNQ1 Voltage Sensor Domain (Q1-VSD) in Lipid Bilayers Using Electron Paramagnetic Resonance Spectroscopy., Dixit G., Biochemistry. February 19, 2019; 58 (7): 965-973.


ML277 specifically enhances the fully activated open state of KCNQ1 by modulating VSD-pore coupling., Hou P., Elife. July 22, 2019; 8                     


Molecular Mechanism of Autosomal Recessive Long QT-Syndrome 1 without Deafness., Oertli A., Int J Mol Sci. January 23, 2021; 22 (3):             


Virus-Host Interactions of Enteroviruses and Parvovirus B19 in Myocarditis., Ho HT., Cell Physiol Biochem. November 18, 2021; 55 (6): 679-703.        


Functional Characterization of a Spectrum of Novel Romano-Ward Syndrome KCNQ1 Variants., Rinné S., Int J Mol Sci. January 10, 2023; 24 (2):                       


Mechanistic insights into robust cardiac IKs potassium channel activation by aromatic polyunsaturated fatty acid analogues., Bohannon BM., Elife. June 23, 2023; 12

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