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Results 1 - 50 of 214 results

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Line Name Species Mutated Gene Description Availability
Xtr.zmym4emNXR X. tropicalis zmym4 CRISPR KO of zmym4 (zinc finger MYM-type containing 4) in X. tropicalis. Germline transmission confi...
Xtr.zeb2emNXR X. tropicalis zeb2 CRISPR KO of zeb2 (zinc finger E-box binding homeobox 2), a gene associated with Mowat-Wilson syndro...
Xtr.zbtb21emHorb X. tropicalis zbtb21 CRISPR knockout of zbtb21(zinc finger and BTB domain containing 21), Current mosaic founders, Not te...
Xtr.zbtb14emHorb X. tropicalis zbtb14 CRISPR knockout of zbtb14 (zinc finger and BTB domain containing 14). Germ line transmission confirm...
Xtr.ywhazemNXR X. tropicalis ywhaz CRISPR KO of ywhaz (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta). ge...
Xtr.xbp1emNXR X. tropicalis xbp1 CRISPR KO of xbp1 ( X-box binding protein 1 ) a gene assocaited with Major Affected Disorder in huma...
Xtr.wwoxemHorb X. tropicalis wwox CRISPR knockout of wwox (WW domain containing oxidoreductase), a gene associated with esophageal can...
Xtr.wt1emHorb X. tropicalis wt1 CRISPR knockout of wt1 (Wilms tumor 1). Germ line transmission confirmed. Animals carry a 5bp deleti...
Xtr.wnt11bemNXR X. tropicalis wnt11b CRISPR knockout of wnt11b (wingless-type MMTV integration site family, member 11B ), Germ line tran...
Xtr.wbp11emNXR X. tropicalis wbp11 CRISPR knockout of wbp11 (WW domain binding protein 11). Germline transmission confirmed, F2s growin...
Xtr.vwa2emNXR X. tropicalis vwa2 CRISPR knock out of vwa2 (von Willebrand factor A domain containing 2 ). Germ line transmission conf...
Xtr.vangl2emNXR X. tropicalis vangl2 CRISPR knockout of vangl2 (VANGL planar cell polarity protein 2 ), a gene associated with neural tub...
Xtr.unc45bmZimml X. tropicalis unc45b Mutation affecting striated muscle identified in the Mill Hill screen for ENU-induced mutations.
Xtr.tyremNXR X. tropicalis tyr CRISPR knockout of tyr (tyrosinase), Confirmed germline transmission. Animal carry a 241bp insertion...
Xtr.tupmZimml X. tropicalis unknown Mutation affecting axial development identified in the Mill Hill screen of ENU-induced mutations.
Xtr.tspan8em3Horb X. tropicalis tspan8 CRISPR knockout of tspan8 (tetraspanin 8), Germ line transmission confirmed. 3rd of 3 tspan lines at...
Xtr.tspan8em2Horb X. tropicalis tspan8 CRISPR knockout of tspan8 (tetraspanin 8), Germ line transmission confirmed. 2nd of 3 tspan lines at...
Xtr.tspan8em1Horb X. tropicalis tspan8 CRISPR knockout of tspan8 (tetraspanin 8), Germ line transmission confirmed. 1of 3 tspan lines at th...
Xtr.tp53em_del2/+_Vlemx X. tropicalis tp53 Deletion is expected to give rise to nonsense-mediated decay since due to the frame-shifting deletio...
Xtr.tp53em_del1/em_del2_Vlemx X. tropicalis tp53 Two types of F1 tp53 heterozygotes, each with a distinct variant of a deletion (em_del1/+ and em_del...
Xtr.tp53em_del1/+_Vlemx X. tropicalis tp53 Deletion is expected to give rise to nonsense-mediated decay since due to the frame-shifting deleti...
Xtr.tlx3em2Horb X. tropicalis tlx3 CRISPR mutant line targeting tlx3 (T cell leukemia homeobox 3). Germ lIne transmission was confirmed...
Xtr.tlx3em1Horb X. tropicalis tlx3 CRISPR knockout of tlx3 (T cell leukemia homeobox 3). Confirmed germline transmission. Custom mutant...
Xtr.thratmShiyb X. tropicalis thra This line was created using TALENS targeting exon 4 (the third coding exon) of the X. tropicalis thr...
Xtr.Tg(mlc2:dnfosl1-eGFP)Qi X. tropicalis fosl1 Fosl1 protein was mutated and truncated to generate 3 mutant polypeptides which then cloned into pc...
Xtr.tdrd1emNXR X. tropicalis tdrd1 CRISPR knockout of tdrd1 (tudor domain containing 1). Germline transmission not yet confirmed. growi...
Xtr.tbxtemJcsm X. tropicalis tbxt Talen-induced 2bp deletion in exon 1 of tbxt (T-box transcription factor T) gene. Mutation destroys ...
Xtr.tbxt.2em2Jcsm X. tropicalis tbxt.2 Talen-induced mutant line. Talen-induced 7-bp deletion in third exon of T, brachyury homolog, gene ...
Xtr.tbxt.2em1Jcsm X. tropicalis tbxt.2 Talen-mediated mutant line. Talen-induced 7-bp deletion in third exon of T, brachyury homolog, gene ...
Xtr.tbxt,tbxt.2emJcsm X. tropicalis tbxt Double talen-induced mutant line. Talen induced 2-bp deletion in exon 1 of tbxt and 7 bp deletion in...
Xtr.tbx5emHorb X. tropicalis tbx5 CRISPR knockout of tbx5 (T-box 5 ), Confirmed germline transmission. Custom mutant generated by Horb...
Xtr.tbx2emHorb X. tropicalis tbx2 CRISPR knockout of tbx2 (T-box 2), Current mosaic founders, Not tested for germline transmission.
Xtr.supt5hmZimml X. tropicalis supt5h Mutation affecting eye development and melanophore migration identified in the Mill Hill screen for ...
Xtr.srd5a3emNXR X. tropicalis srd5a3 CRISPR knockout of srd5a3 (steroid 5 alpha-reductase 3), Germ line transmission not yet confirmed. C...
Xtr.srd5a2emNXR X. tropicalis srd5a2 CRISPR knockout of srd5a2 (steroid 5 alpha-reductase 2), Confirmed germ line transmission. animals c...
Xtr.sox3emHorb X. tropicalis sox3 CRISPR knockout of sox3 (SRY-box 3), Current mosaic founders, Not tested for germline transmission. ...
Xtr.sox2emHorb X. tropicalis sox2 CRISPR knockout of sox2 (SRY-box 2). Germ line transmission confirmed. Animals carry a 1bp insertion...
Xtr.snai2emNXR X. tropicalis snai2 CRISPR knockout of snai2 (snail family zinc finger 2) in X. tropicalis. Germ line transmission confi...
Xtr.snai1emNXR X. tropicalis snai1 CRISPR knockout of snai1 (snail family zinc finger 1) in X. tropicalis. germline transmission confir...
Xtr.smad4mZimml X. tropicalis smad4 Mutation affecting haematopoiesis identified in a screen for ENU-induced mutations at Mill Hill. Pos...
Xtr.six1em2NXR X. tropicalis six1 CRISPR knockout of six1 (SIX homeobox 1), a gene associated with branchiootorenal syndrome and branc...
Xtr.six1em1NXR X. tropicalis six1 CRISPR knockout of six1 (SIX homeobox 1), a gene associated with branchiootorenal syndrome and branc...
Xtr.shroom3emHorb X. tropicalis shroom3 CRISPR knockout of shroom3 (shroom family member 3), Current mosaic founders, Germ line transmissio...
Xtr.sf3b4emNXR X. tropicalis sf3b4 CRISPR knockout of sf3b4 (splicing factor 3b subunit 4) in X tropicalis. sf3b4 is a gene associated ...
Xtr.rxrgemHorb X. tropicalis rxrg Description: CRISPR knockout of rxrg (retinoid X receptor gamma). Confirmed germline transmission. C...
Xtr.rxrbemHorb X. tropicalis rxrb CRISPR knockout of rxrb (retinoid X receptor beta). Confirmed germline transmission. Animals carry a...
Xtr.rxraemNXR X. tropicalis rxra CRISPR knockout of rxra (retinoid X receptor alpha ). Germ line transmission confirmed. Contact NXR...
Xtr.runx2emHorb X. tropicalis runx2 CRISPR knockout of runx2 (runt related transcription factor 2). Contact NXR to inquire about availab...
Xtr.runx1em3NXR X. tropicalis runx1 CRISPR knockout of runx1(runt related transcription factor 1). Germ line transmission confirmed. Ani...
Xtr.runx1em2NXR X. tropicalis runx1 CRISPR knockout of runx1(runt related transcription factor 1). Germ line transmission confirmed. Ani...

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