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XB-ANTIBODY-25874711
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Antibody Name:
Mapk1/3 Ab20
Common Name: Phospho-p44/42 MAPK RRID: AB_331775 Synonyms: 4377s, 4377t, erk1/2
Source: Cell Signaling Technology |
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| Antibody | |
| Clone Number | |
| Purification | Affinity Purification |
| Isotype | IgG |
| Host Organism | rabbit |
| Xenopus Reactivity | X. tropicalis, X. laevis |
| Non-Xenopus Reactivity | fruitfly, human, monkey, mouse, pig, rat, zebrafish |
| Description: | Mitogen-activated protein kinases (MAPKs) are a widely conserved family of serine/threonine protein kinases involved in many cellular programs, such as cell proliferation, differentiation, motility, and death. The p44/42 MAPK (Erk1/2) signaling pathway can be activated in response to a diverse range of extracellular stimuli including mitogens, growth factors, and cytokines (1-3), and research investigators consider it an important target in the diagnosis and treatment of cancer |
| Immunogen | |
| Name | mapk |
| Type | synthetic sequence |
| Post Translational Modifications | Phosphorylated |
| Source Organism | human |
| Description | Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Thr202/Tyr204 of human p44 MAP kinase. |
| Sequence | |
| Reported Usage | |
| western blot | 1:1000 |
| immunofluorescence | 1:200 |
| flow cytometry | 1:200-1:800 |
| Publications | |
| ???displayAntibody.papersFirst??? |
Injury-induced Erk1/2 signaling tissue-specifically interacts with Ca2+ activity and is necessary for regeneration of spinal cord and skeletal muscle., Cell Calcium 2022  |
| ???displayAntibody.papersRecent??? | |
| ???displayAntibody.papersAll??? | |
